Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.38 |
| ▸ | DGKA | P23743 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989603 | 1.00 | TSHR (0.67) | TSHRCES2NAAATHRBEPHX1 | |
| SCHEMBL15284836 | 1.00 | TSHR (0.67) | TSHRCES2NAAATHRBEPHX1 | |
| SCHEMBL28059477 | 1.00 | TSHR (0.67) | TSHRCES2NAAATHRBEPHX1 | |
| SCHEMBL28055228 | 0.98 | TSHR (0.63) | TSHRCES2NAAATHRBEPHX1 | |
| Phosphoric Acid SCHEMBL10797258 | 0.93 | TSHR (0.59) | TSHRCES2NAAATHRBEPHX1 | |
| Phosphoric Acid SCHEMBL10719083 | 0.93 | TSHR (0.59) | TSHRCES2NAAATHRBEPHX1 | |
| Phosphoric Acid SCHEMBL10716498 | 0.93 | TSHR (0.59) | TSHRCES2NAAATHRBEPHX1 | |
| SCHEMBL10517884 | 0.92 | TSHR (0.55) | TSHRCES2NAAATHRBDGKA | |
| SCHEMBL2946008 | 0.92 | TSHR (0.53) | TSHRCES2NAAATHRBALDH1A1 | |
| SCHEMBL31616825 | 0.86 | TSHR (0.59) | TSHRCES2NAAATHRBEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158728-B2 | Methods and materials for fabricating microfluidic devices | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2012-04-17 | — | — | US | disclosed |
| US-20090281250-A1 | METHODS AND MATERIALS FOR FABRICATING MICROFLUIDIC DEVICES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) | 2009-11-12 | — | — | US | disclosed |