Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.46 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.46 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphoric Acid SCHEMBL10716498 | 1.00 | TSHR (0.59) | TSHRLPAR3LPAR2LPAR1CES2 | |
| Phosphoric Acid SCHEMBL10719083 | 1.00 | TSHR (0.59) | TSHRLPAR3LPAR2LPAR1CES2 | |
| Phosphoric Acid SCHEMBL10716548 | 0.93 | TSHR (0.49) | TSHRLPAR3LPAR2LPAR1THRB | |
| SCHEMBL1753657 | 0.93 | TSHR (0.67) | TSHRLPAR3LPAR2LPAR1CES2 | |
| SCHEMBL28059477 | 0.93 | TSHR (0.67) | TSHRLPAR3LPAR2LPAR1CES2 | |
| SCHEMBL15284836 | 0.93 | TSHR (0.67) | TSHRLPAR3LPAR2LPAR1CES2 | |
| SCHEMBL8989603 | 0.93 | TSHR (0.67) | TSHRLPAR3LPAR2LPAR1CES2 | |
| SCHEMBL28055228 | 0.91 | TSHR (0.63) | TSHRLPAR3LPAR2LPAR1CES2 | |
| SCHEMBL10517884 | 0.86 | TSHR (0.55) | TSHRCES2NAAATHRB | |
| SCHEMBL2946008 | 0.86 | TSHR (0.53) | TSHRCES2NAAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4701375-A | TOPCOAT OF LUBRICANTS AND ANTIOXIDANT OF PHOSPHORIC ESTER; CURABLE BY RADIATION | TDK CORPORATION (JP) | 1987-10-20 | — | — | US | disclosed |