Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8989603 | 0.92 | TSHR (0.67) | TSHRALDH1A1THRBCES2NAAA | |
| SCHEMBL15284836 | 0.92 | TSHR (0.67) | TSHRALDH1A1THRBCES2NAAA | |
| SCHEMBL1753657 | 0.92 | TSHR (0.67) | TSHRALDH1A1THRBCES2NAAA | |
| SCHEMBL28059477 | 0.92 | TSHR (0.67) | TSHRALDH1A1THRBCES2NAAA | |
| SCHEMBL28055228 | 0.90 | TSHR (0.63) | TSHRALDH1A1THRBCES2NAAA | |
| SCHEMBL730172 | 0.90 | TSHR (0.63) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL28516066 | 0.88 | ALDH1A1 (0.48) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL10517884 | 0.87 | TSHR (0.55) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL11207672 | 0.87 | TSHR (0.41) | TSHRALDH1A1THRBTDP1POLB | |
| SCHEMBL15191562 | 0.86 | LPAR3 (0.50) | TSHRTHRBTDP1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7764855-B2 | Optical fiber with cured polymeric coating | PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) | 2010-07-27 | — | — | US | claimed |
| US-20070263972-A1 | Optical Fiber with Cured Polymeric Coating | PIRELLI & C. S.P.A. (IT) | 2007-11-15 | — | — | US | claimed |
| US-7764855-B2 | Optical fiber with cured polymeric coating | PRYSMIAN CAVI E SISTEMI ENERGIA S.R.L. (IT) | 2010-07-27 | — | — | US | disclosed |
| US-20070263972-A1 | Optical Fiber with Cured Polymeric Coating | PIRELLI & C. S.P.A. (IT) | 2007-11-15 | — | — | US | disclosed |