Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.57 |
| ▸ | CTSD | P07339 | 4/20 | 0.54 |
| ▸ | BACE1 | P56817 | 4/20 | 0.54 |
| ▸ | GNPAT | O15228 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17536609 | 1.00 | ALDH1A1 (0.60) | ALDH1A1FOLH1CTSDBACE1GNPAT | |
| SCHEMBL21049237 | 1.00 | ALDH1A1 (0.60) | ALDH1A1FOLH1CTSDBACE1GNPAT | |
| SCHEMBL21049238 | 1.00 | ALDH1A1 (0.60) | ALDH1A1FOLH1CTSDBACE1GNPAT | |
| SCHEMBL17951689 | 0.99 | ALDH1A1 (0.58) | ALDH1A1FOLH1CTSDBACE1GNPAT | |
| SCHEMBL16557150 | 0.94 | ALDH1A1 (0.65) | ALDH1A1FOLH1CTSDBACE1LMNA | |
| SCHEMBL16557153 | 0.92 | ALDH1A1 (0.54) | ALDH1A1FOLH1CTSDBACE1CTSB | |
| SCHEMBL20255738 | 0.90 | CTSD (0.50) | ALDH1A1FOLH1CTSDBACE1CTSB | |
| SCHEMBL21012039 | 0.90 | CTSD (0.50) | ALDH1A1FOLH1CTSDBACE1CTSB | |
| SCHEMBL7109161 | 0.89 | GNPAT (0.50) | ALDH1A1FOLH1CTSDBACE1GNPAT | |
| SCHEMBL7109159 | 0.89 | GNPAT (0.50) | ALDH1A1FOLH1CTSDBACE1GNPAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10314894-B2 | Treatment of cardio-renal disease using PCSK6 | THE CLEVELAND CLINIC FOUNDATION (US) | 2019-06-11 | — | — | US | disclosed |
| US-20160058848-A1 | TREATMENT OF CARDIO-RENAL DISEASE USING PCSK6 | THE CLEVELAND CLINIC FOUNDATION | 2016-03-03 | — | — | US | disclosed |
| CN-103221069-A | Alumina nanoparticle bioconjugates and methods of stimulating an immune response using said bioconjugates | PROVIDENCE HEALTH & SERVICES OREGON | 2013-07-24 | — | — | CN | disclosed |