Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 14/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MLNR | O43193 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12391406 | 1.00 | PDK2 (0.40) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL22950645 | 0.97 | PDK2 (0.38) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL18802561 | 0.96 | PDK2 (0.39) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL22401922 | 0.96 | PDK2 (0.38) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL6372460 | 0.96 | ALDH1A1 (0.37) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL13907780 | 0.96 | PDK2 (0.41) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL14340056 | 0.96 | PDK2 (0.43) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL20707545 | 0.96 | PDK2 (0.43) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL5531723 | 0.96 | ALDH1A1 (0.39) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 | |
| SCHEMBL14340216 | 0.96 | PDK2 (0.43) | PDK2ALDH1A1L3MBTL1KDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120168739-A1 | FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE | CANON KABUSHIKI KAISHA (JP) | 2012-07-05 | — | — | US | disclosed |
| US-20120168739-A1 | FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE | CANON KABUSHIKI KAISHA (JP) | 2012-07-05 | — | — | US | disclosed |
| US-8158835-B2 | Fluorene compound and organic electroluminescence device | CANON KABUSHIKI KAISHA (JP) | 2012-04-17 | — | — | US | disclosed |
| US-8158835-B2 | Fluorene compound and organic electroluminescence device | CANON KABUSHIKI KAISHA (JP) | 2012-04-17 | — | — | US | disclosed |
| US-20090200919-A1 | FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE | CANON KABUSHIKI KAISHA (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090200919-A1 | FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE | CANON KABUSHIKI KAISHA (JP) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120168739-A1 | FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE | AFF1, LEF1, AFF2 | PDK2 1601/4885ALDH1A1 391/4885L3MBTL1 2837/4885 |
| US-20090200919-A1 | FLUORENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE | AFF1, LEF1, AFF2 | PDK2 1601/4885ALDH1A1 391/4885L3MBTL1 2837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.