SCHEMBL17536896

SCHEMBL17536896

Cc1ccc(-c2ccc3c4ccc(-c5ccc(C)c(-c6cccc(-c7ccccc7)c6)c5)cc4c4ccccc4c3c2)cc1-c1cccc(-c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 1/20 0.41
KDM4E B2RXH2 1/20 0.41
HSD17B1 P14061 2/20 0.37
HSD17B2 P37059 2/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
APAF1 O14727 1/20 0.37
NPC1 O15118 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
XBP1 P17861 1/20 0.37
PTBP1 P26599 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
GALK1 P51570 1/20 0.37
BLM P54132 1/20 0.37
SMAD3 P84022 1/20 0.37
ATM Q13315 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17536894 1.00 TNKS2 (0.41) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17536915 0.96 TNKS2 (0.44) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17536906 0.95 KDM4E (0.45) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17536895 0.93 TNKS2 (0.44) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17536897 0.93 TNKS2 (0.44) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17536917 0.89 TNKS2 (0.40) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17057274 0.87 TYMS (0.39) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17057273 0.87 TNKS2 (0.35) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17263370 0.86 HSD17B1 (0.49) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17263371 0.86 KDM4E (0.39) TNKS2KDM4EHSD17B1HSD17B2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9944846-B2 Compositions for electronic applications E I DU PONT DE NEMOURS AND COMPANY (US) 2018-04-17 US disclosed
US-20160060512-A1 COMPOSITIONS FOR ELECTRONIC APPLICATIONS LG CHEM, LTD. (KR) 2016-03-03 US disclosed
WO-2016033167-A1 COMPOSITIONS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-03-03 WO disclosed