SCHEMBL17536897

SCHEMBL17536897

Cc1ccc(-c2ccc3c4ccc(-c5ccc(C)c(-c6ccc(-c7ccccc7)cc6)c5)cc4c4ccccc4c3c2)cc1-c1ccc(-c2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS2 Q9H2K2 1/20 0.44
KDM4E B2RXH2 1/20 0.42
HSD17B1 P14061 1/20 0.39
HSD17B2 P37059 1/20 0.39
HPRT1 P00492 1/20 0.39
ESR2 Q92731 1/20 0.39
MEN1 O00255 1/20 0.39
APAF1 O14727 1/20 0.39
NPC1 O15118 1/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
THRB P10828 1/20 0.39
XBP1 P17861 1/20 0.39
PTBP1 P26599 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
GALK1 P51570 1/20 0.39
BLM P54132 1/20 0.39
SMAD3 P84022 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17536895 1.00 TNKS2 (0.44) TNKS2KDM4EHSD17B1HSD17B2HPRT1
SCHEMBL17536915 0.96 TNKS2 (0.44) TNKS2KDM4EHSD17B1HSD17B2HPRT1
SCHEMBL17536906 0.95 KDM4E (0.45) TNKS2KDM4EHSD17B1HSD17B2HPRT1
SCHEMBL17536894 0.93 TNKS2 (0.41) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17536896 0.93 TNKS2 (0.41) TNKS2KDM4EHSD17B1HSD17B2MEN1
SCHEMBL17536898 0.89 NPC1 (0.41) TNKS2KDM4EHSD17B1HSD17B2HPRT1
SCHEMBL7930011 0.88 L3MBTL1 (0.47) TNKS2KDM4EHPRT1ESR2MEN1
SCHEMBL20407282 0.85 CA12 (0.46) TNKS2KDM4ELMNACYP1A2CYP3A4
SCHEMBL17536903 0.84 KDM4E (0.45) TNKS2KDM4EESR2CYP1A2CYP3A4
SCHEMBL17263371 0.82 KDM4E (0.39) TNKS2KDM4EHSD17B1HSD17B2MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9944846-B2 Compositions for electronic applications E I DU PONT DE NEMOURS AND COMPANY (US) 2018-04-17 US disclosed
US-20160060512-A1 COMPOSITIONS FOR ELECTRONIC APPLICATIONS LG CHEM, LTD. (KR) 2016-03-03 US disclosed
WO-2016033167-A1 COMPOSITIONS FOR ELECTRONIC APPLICATIONS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2016-03-03 WO disclosed