Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPC5 | Q9UL62 | 4/20 | 0.41 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | CFTR | P13569 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDE2A | O00408 | 2/20 | 0.31 |
| ▸ | PDE1A | P54750 | 2/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | PDE5A | O76074 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17509579 | 0.88 | TRPC5 (0.41) | TRPC5MAOAMAOBCFTRTDP1 | |
| SCHEMBL17509570 | 0.87 | TRPC5 (0.40) | TRPC5MAOAMAOBCFTRTDP1 | |
| SCHEMBL17509576 | 0.83 | TRPC5 (0.55) | TRPC5MAOAMAOBTDP1LMNA | |
| SCHEMBL17538648 | 0.80 | TRPC5 (0.49) | TRPC5MAOAMAOBTDP1KMT2A | |
| SCHEMBL17509554 | 0.77 | TRPC5 (0.49) | TRPC5LMNA | |
| SCHEMBL17509559 | 0.77 | TRPC5 (0.41) | TRPC5MAOAMAOB | |
| SCHEMBL17538691 | 0.77 | TRPC5 (0.35) | TRPC5TDP1KMT2ACYP3A4 | |
| SCHEMBL17509575 | 0.74 | TRPC5 (0.44) | TRPC5KMT2AADORA2B | |
| SCHEMBL17508800 | 0.73 | TRPC5 (0.76) | TRPC5KMT2ACYP1A2CYP3A4TSHR | |
| SCHEMBL17509081 | 0.73 | TRPC5 (0.53) | TRPC5MAOAMAOBADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016023830-A1 | PYRIDO[2,3-D]PYRIMIDINE-2,4(1H,3H)-DIONE DERIVATIVES | HYDRA BIOSCIENCES, INC. (US) | 2016-02-18 | — | — | WO | disclosed |