SCHEMBL1753872

SCHEMBL1753872

CCCCCNC(=O)C1CCCC1

nearest known ligand 0.93

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.93
GNAI3 P08754 2/20 0.68
GNAO1 P09471 2/20 0.68
GNAI1 P63096 2/20 0.68
EPHX1 P07099 8/20 0.57
PRCP P42785 2/20 0.57
EPHX2 P34913 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15189057 0.98 NAAA (0.96) NAAAGNAI3GNAO1GNAI1EPHX1
SCHEMBL4555028 0.98 NAAA (0.96) NAAAGNAI3GNAO1GNAI1EPHX1
SCHEMBL28082885 0.96 NAAA (1.00) NAAAGNAI3GNAO1GNAI1EPHX1
SCHEMBL28082415 0.96 NAAA (1.00) NAAAGNAI3GNAO1GNAI1EPHX1
Cyclohexanecarboxylic Acid Pentadecylamide SCHEMBL28082344 0.96 NAAA (1.00) NAAAGNAI3GNAO1GNAI1EPHX1
SCHEMBL8847632 0.96 NAAA (1.00) NAAAGNAI3GNAO1GNAI1EPHX1
SCHEMBL28832373 0.96 NAAA (1.00) NAAAGNAI3GNAO1GNAI1EPHX1
SCHEMBL17694453 0.96 NAAA (1.00) NAAAGNAI3GNAO1GNAI1EPHX1
SCHEMBL6267383 0.96 NAAA (1.00) NAAAGNAI3GNAO1GNAI1EPHX1
SCHEMBL28082824 0.96 NAAA (1.00) NAAAGNAI3GNAO1GNAI1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846710-B2 Method of preferentially inducing the biosynthesis of interferon 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-30 US disclosed
US-8846710-B2 Method of preferentially inducing the biosynthesis of interferon 3M INNOVATIVE PROPERTIES COMPANY (US) 2014-09-30 US disclosed
US-8158794-B2 Hydroxyalkyl substituted imidazoquinoline compounds and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-04-17 US disclosed
US-8158794-B2 Hydroxyalkyl substituted imidazoquinoline compounds and methods 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-04-17 US disclosed
US-20090069314-A1 Hydroxyalkyl Substituted Imidazoquinoline Compounds and Methods COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-03-12 US disclosed
US-20090069314-A1 Hydroxyalkyl Substituted Imidazoquinoline Compounds and Methods COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-03-12 US disclosed
US-20090030031-A1 Method of Preferentially Inducing the Biosynthesis of Interferon COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-01-29 US disclosed
US-20090030031-A1 Method of Preferentially Inducing the Biosynthesis of Interferon COLEY PHARMACEUTICAL GROUP, INC. (US) 2009-01-29 US disclosed
US-20070037824-A1 Enzyme inhibitors from pyrazolo[1,5a]pyrimidine as enzyme inhibitors SCHERING CORPORATION 2007-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090030031-A1 Method of Preferentially Inducing the Biosynthesis of Interferon IFNG, IFNAR1, EIF2AK2 NAAA 1634/4885GNAI3 965/4885GNAO1 1640/4885
US-20090069314-A1 Hydroxyalkyl Substituted Imidazoquinoline Compounds and Methods IFNG, IRF3, IFNAR1 NAAA 2734/4885GNAI3 450/4885GNAO1 1309/4885
US-20070037824-A1 Enzyme inhibitors from pyrazolo[1,5a]pyrimidine as enzyme inhibitors CDK2, CDK5, CDKN1A NAAA 1091/4885GNAI3 1775/4885GNAO1 1590/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.