SCHEMBL175389

SCHEMBL175389

Cc1ccc(C=C(c2ccc(C)cc2)c2ccccc2Nc2ccc(Nc3ccccc3C(=Cc3ccc(C)cc3)c3ccc(C)cc3)c3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 3/20 0.44
CDC25B P30305 9/20 0.41
CDC25A P30304 1/20 0.36
CDC25C P30307 1/20 0.36
AKR1C3 P42330 1/20 0.36
AKR1C2 P52895 1/20 0.36
NPC1 O15118 3/20 0.36
RAB9A P51151 3/20 0.36
KDM4E B2RXH2 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
POLB P06746 2/20 0.36
ALDH1A1 P00352 2/20 0.36
MEN1 O00255 1/20 0.36
LMNA P02545 1/20 0.36
KMT2A Q03164 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
ESR1 P03372 2/20 0.35
MAPT P10636 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10718203 0.82 PTGS2 (0.48) PTGS2AKR1C3AKR1C2NPC1RAB9A
SCHEMBL6014203 0.79 NPC1 (0.46) PTGS2AKR1C3AKR1C2NPC1RAB9A
SCHEMBL6014206 0.79 NPC1 (0.46) PTGS2AKR1C3AKR1C2NPC1RAB9A
SCHEMBL3454646 0.77 PTGS2 (0.48) PTGS2AKR1C3NPC1RAB9AKDM4E
SCHEMBL9026538 0.71 PTGS2 (0.73) PTGS2NPC1RAB9AKDM4EPOLB
SCHEMBL9026535 0.71 PTGS2 (0.73) PTGS2NPC1RAB9AKDM4EPOLB
SCHEMBL8053369 0.71 PTGS2 (0.69) PTGS2KDM4ESMN1; SMN2ALDH1A1MEN1
SCHEMBL2925327 0.71 PTGS2 (0.69) PTGS2KDM4ESMN1; SMN2ALDH1A1MEN1
SCHEMBL5047517 0.71 PTGS2 (0.51) PTGS2AKR1C3NPC1RAB9AKDM4E
SCHEMBL9806382 0.69 PTGS2 (0.70) PTGS2NPC1RAB9AKDM4EPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1517589-B1 Substrate of emitting device and emitting device using the same SAMSUNG MOBILE DISPLAY CO LTD (KR) 2012-03-07 EP disclosed
US-7638797-B2 Substrate of emitting device and emitting device using the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2009-12-29 US disclosed
US-20080265245-A1 SUBSTRATE OF EMITTING DEVICE AND EMITTING DEVICE USING THE SAME SAMSUNG SDI CO., LTD. (KR) 2008-10-30 US disclosed
US-7391048-B2 Optical control portion with graded metal dopant to control refractive index SAMSUNG SDI CO., LTD. (KR) 2008-06-24 US disclosed
EP-1517589-A1 Substrate of emitting device and emitting device using the same Samsung SDI Co., Ltd. (KR) 2005-03-23 EP disclosed
US-20050051791-A1 Substrate of emitting device and emitting device using the same SAMSUNG DISPLAY CO., LTD. (KR) 2005-03-10 US disclosed