Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SIRT2 | Q8IXJ6 | 3/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | FABP4 | P15090 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6014206 | 1.00 | NPC1 (0.46) | NPC1RAB9ASIRT2PTGS2MAPT | |
| SCHEMBL10718203 | 0.94 | PTGS2 (0.48) | NPC1RAB9ASIRT2PTGS2MAPT | |
| SCHEMBL6820125 | 0.85 | HPGD (0.57) | NPC1RAB9APTGS2MAPTGAA | |
| SCHEMBL10745106 | 0.84 | CXCR2 (0.41) | PTGS2MAPTHPGDMEN1KMT2A | |
| SCHEMBL2528717 | 0.83 | PTGS2 (0.57) | NPC1RAB9APTGS2MAPTHPGD | |
| SCHEMBL13007203 | 0.82 | PTGS2 (0.53) | NPC1RAB9APTGS2MAPTGAA | |
| SCHEMBL2528716 | 0.82 | PTGS2 (0.59) | NPC1RAB9APTGS2MAPTGAA | |
| SCHEMBL10745097 | 0.79 | MAPT (0.50) | NPC1RAB9APTGS2MAPTHPGD | |
| SCHEMBL175389 | 0.79 | PTGS2 (0.44) | NPC1RAB9APTGS2MAPTHPGD | |
| SCHEMBL17997457 | 0.79 | PTGS2 (0.50) | NPC1RAB9APTGS2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7112392-B2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge for image forming apparatus using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2006-09-26 | — | — | US | disclosed |
| US-20040170911-A1 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge for image forming apparatus using the electrophotographic photoreceptor | RICOH COMPANY, LTD. (JP) | 2004-09-02 | — | — | US | disclosed |
| EP-1291723-A2 | Electrophotographic photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor | Ricoh Company, Ltd. (JP) | 2003-03-12 | — | — | EP | disclosed |