Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 0.37 |
| ▸ | FGF2 | P09038 | 2/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17539599 | 0.81 | FGFR1 (0.36) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539447 | 0.78 | FGFR1 (0.49) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539448 | 0.78 | FGFR1 (0.42) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539645 | 0.77 | FGFR1 (0.46) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539484 | 0.77 | GRM5 (0.35) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539636 | 0.77 | FGFR1 (0.41) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539488 | 0.76 | FGFR1 (0.50) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539515 | 0.76 | FGFR1 (0.50) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539662 | 0.76 | FGFR1 (0.44) | FGFR1FGF2FGFR4FGFR3 | |
| SCHEMBL17539501 | 0.76 | FGFR1 (0.51) | FGFR1FGF2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016027780-A1 | 4-AMINOPYRIDINE DERIVATIVE | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 2016-02-25 | — | — | WO | disclosed |