Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | USP2 | O75604 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | TSHR | P16473 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | NAMPT | P43490 | 1/20 | 0.56 |
| ▸ | VNN1 | O95497 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 2/20 | 0.55 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.55 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22972394 | 0.90 | NPSR1 (0.64) | NPSR1ALDH1A1L3MBTL1USP2CA2 | |
| SCHEMBL13504066 | 0.84 | NPSR1 (0.60) | NPSR1ALDH1A1L3MBTL1USP2CA2 | |
| SCHEMBL21246563 | 0.84 | NPSR1 (0.62) | NPSR1ALDH1A1L3MBTL1USP2CA2 | |
| SCHEMBL5783915 | 0.82 | HTT (0.71) | NPSR1ALDH1A1L3MBTL1CA2HTT | |
| SCHEMBL3592277 | 0.82 | POLB (0.63) | NPSR1ALDH1A1L3MBTL1USP2CA2 | |
| SCHEMBL11628250 | 0.82 | NPSR1 (0.67) | NPSR1ALDH1A1L3MBTL1USP2HTT | |
| SCHEMBL30491866 | 0.82 | NPSR1 (0.67) | NPSR1ALDH1A1L3MBTL1USP2HTT | |
| SCHEMBL5257811 | 0.81 | LMNA (0.72) | NPSR1ALDH1A1CA2HTTLMNA | |
| SCHEMBL19623369 | 0.79 | ALDH1A1 (0.78) | NPSR1ALDH1A1L3MBTL1USP2HTT | |
| SCHEMBL7082686 | 0.79 | TSHR (0.73) | NPSR1ALDH1A1USP2CA2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2103613-B1 | QUINOXALINE DERIVATIVE | ASKA PHARM CO LTD (JP) | 2016-02-17 | — | — | EP | disclosed |