SCHEMBL17540334

SCHEMBL17540334

Nc1ccc(C(=O)Nc2ccc3c(O)c(N=Nc4ccc(N=Nc5ccc(N=Nc6ccccc6)cc5)cc4)c(S(=O)(=O)O)cc3c2)cc1

nearest known ligand 0.68

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PRMT3 O60678 1/20 0.68
EP300 Q09472 1/20 0.68
PRMT6 Q96LA8 1/20 0.68
PRMT1 Q99873 1/20 0.68
ENPP2 Q13822 13/20 0.66
CD40 P25942 1/20 0.57
CD40LG P29965 1/20 0.57
CASP6 P55212 1/20 0.57
CTDSP1 Q9GZU7 1/20 0.57
CA2 P00918 1/20 0.48
CA3 P07451 1/20 0.48
PHLPP2 Q6ZVD8 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27100618 0.97 PRMT1 (0.67) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL19234816 0.94 PRMT3 (0.60) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL17540335 0.93 PRMT3 (0.63) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL17540333 0.93 PRMT3 (0.74) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL17545771 0.92 CD40 (0.67) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL17545727 0.92 CD40 (0.67) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL19234837 0.88 PRMT3 (0.54) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL17545732 0.88 ENPP2 (0.74) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL16675028 0.88 ENPP2 (0.74) PRMT3EP300PRMT6PRMT1ENPP2
SCHEMBL10623048 0.88 ENPP2 (0.74) PRMT3EP300PRMT6PRMT1ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed