SCHEMBL17540344

SCHEMBL17540344

Cc1cc(N=Nc2cc(C)c(N=Nc3c(S(=O)(=O)O)cc4cc(Nc5ccccc5)ccc4c3O)cc2C)c(C)cc1N=Nc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 10/20 0.67
PRMT1 Q99873 2/20 0.63
PRMT3 O60678 1/20 0.63
EP300 Q09472 1/20 0.63
PRMT6 Q96LA8 1/20 0.63
PHLPP2 Q6ZVD8 2/20 0.58
CD40 P25942 1/20 0.55
CD40LG P29965 1/20 0.55
ALDH1A1 P00352 2/20 0.48
HIF1A Q16665 2/20 0.48
MEN1 O00255 1/20 0.45
THRB P10828 1/20 0.45
KMT2A Q03164 1/20 0.45
TDP1 Q9NUW8 1/20 0.45
CYP1A2 P05177 1/20 0.45
CARM1 Q86X55 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17515771 1.00 ENPP2 (0.67) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL2615793 0.96 ENPP2 (0.65) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17545761 0.95 ENPP2 (0.69) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17518450 0.95 ENPP2 (0.69) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17540346 0.93 ENPP2 (0.79) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17540345 0.93 ENPP2 (0.79) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL19234941 0.92 ENPP2 (0.68) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL14394261 0.92 ENPP2 (0.68) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL14609146 0.92 ENPP2 (0.68) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17515769 0.92 PRMT1 (0.69) ENPP2PRMT1PRMT3EP300PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170153361-A1 Achromatic Polarizing Plate With High-Transmissivity And High-Degree Of Polarization NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed