SCHEMBL17540346

SCHEMBL17540346

COc1cc(N=Nc2ccccc2)c(C)cc1N=Nc1cc(OC)c(N=Nc2c(S(=O)(=O)O)cc3cc(Nc4ccccc4)ccc3c2O)cc1C

nearest known ligand 0.79

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 10/20 0.79
PRMT1 Q99873 2/20 0.56
PRMT3 O60678 1/20 0.56
EP300 Q09472 1/20 0.56
PRMT6 Q96LA8 1/20 0.56
PHLPP2 Q6ZVD8 3/20 0.52
CD40 P25942 1/20 0.49
CD40LG P29965 1/20 0.49
CARM1 Q86X55 1/20 0.47
MEN1 O00255 1/20 0.46
ALDH1A1 P00352 1/20 0.46
POLB P06746 1/20 0.46
MAPT P10636 1/20 0.46
PKM P14618 1/20 0.46
MAPK1 P28482 1/20 0.46
KMT2A Q03164 1/20 0.46
PTPN1 P18031 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540345 1.00 ENPP2 (0.79) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL2615785 0.97 ENPP2 (0.76) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL19234942 0.96 ENPP2 (0.80) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL16417275 0.96 ENPP2 (0.80) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17545772 0.96 ENPP2 (0.80) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL13556981 0.96 ENPP2 (0.80) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL13287624 0.96 ENPP2 (0.80) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL19958192 0.96 ENPP2 (0.75) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL17540350 0.96 ENPP2 (0.73) ENPP2PRMT1PRMT3EP300PRMT6
SCHEMBL14422684 0.96 ENPP2 (0.80) ENPP2PRMT1PRMT3EP300PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170153361-A1 Achromatic Polarizing Plate With High-Transmissivity And High-Degree Of Polarization NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-06-01 US disclosed
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 US disclosed