SCHEMBL17540349

SCHEMBL17540349

COc1ccccc1N=Nc1cc(OC)c(N=Nc2cc(OC)c(N=Nc3c(S(=O)(=O)O)cc4cc(Nc5ccccc5)ccc4c3O)cc2C)cc1C

nearest known ligand 0.79

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ ENPP2 Q13822 11/20 0.79
▸ PHLPP2 Q6ZVD8 2/20 0.51
▸ PRMT1 Q99873 2/20 0.47
▸ PRMT3 O60678 1/20 0.47
▸ EP300 Q09472 1/20 0.47
▸ PRMT6 Q96LA8 1/20 0.47
▸ PTPN1 P18031 2/20 0.45
▸ ALDH1A1 P00352 1/20 0.43
▸ HIF1A Q16665 1/20 0.43
▸ CD40 P25942 1/20 0.43
▸ CD40LG P29965 1/20 0.43
▸ CARM1 Q86X55 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540348 0.95 ENPP2 (0.79) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL13182922 0.93 ENPP2 (0.76) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL17540346 0.93 ENPP2 (0.79) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL17540345 0.93 ENPP2 (0.79) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL14024923 0.93 ENPP2 (0.85) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL17545810 0.93 ENPP2 (0.83) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL29927435 0.93 ENPP2 (0.78) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL2615785 0.92 ENPP2 (0.76) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL10625284 0.91 ENPP2 (0.76) ENPP2PHLPP2PRMT1PRMT3EP300
SCHEMBL10625271 0.91 ENPP2 (0.73) ENPP2PHLPP2PRMT1PRMT3EP300

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170153361-A1 Achromatic Polarizing Plate With High-Transmissivity And High-Degree Of Polarization NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2017-06-01 — — US disclosed
US-20160041322-A1 Achromatic Polarization Element, And Polarization Plate NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2016-02-11 — — US disclosed
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