SCHEMBL17540420

SCHEMBL17540420

CCn1c2ccccc2c2cc(/C(CCC3CCCCC3)=N/OC(=O)c3ccccc3)ccc21

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.46
PTGER4 P35408 4/20 0.45
KDM4E B2RXH2 3/20 0.43
LMNA P02545 3/20 0.43
MAPT P10636 2/20 0.43
RORC P51449 1/20 0.43
CNR2 P34972 5/20 0.42
ALDH1A1 P00352 3/20 0.41
HPGD P15428 2/20 0.41
MEN1 O00255 1/20 0.41
KMT2A Q03164 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
POLB P06746 1/20 0.41
MAPK1 P28482 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540437 0.91 NPC1 (0.48) NPC1PTGER4KDM4ELMNAMAPT
SCHEMBL17540436 0.89 NPC1 (0.45) NPC1PTGER4KDM4ELMNAMAPT
SCHEMBL19632274 0.88 CNR2 (0.38) NPC1PTGER4KDM4ELMNAMAPT
SCHEMBL28881747 0.88 PTGER4 (0.38) NPC1PTGER4KDM4ELMNACNR2
SCHEMBL19632430 0.88 PTGER4 (0.38) NPC1PTGER4KDM4ELMNACNR2
SCHEMBL29874784 0.88 PTGER4 (0.38) NPC1PTGER4KDM4ELMNACNR2
SCHEMBL17540422 0.88 NPC1 (0.37) NPC1PTGER4LMNAMAPTALDH1A1
SCHEMBL19439766 0.86 CNR2 (0.42) NPC1PTGER4KDM4ELMNAMAPT
SCHEMBL17540443 0.84 PTGER4 (0.47) PTGER4KDM4ELMNAMAPTCNR2
SCHEMBL21610323 0.81 NPC1 (0.53) NPC1PTGER4KDM4ELMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3002632-B1 ACRYLIC PHOTOCURABLE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONICS MAT CO LTD (CN) 2018-03-28 EP disclosed
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
EP-3002632-A1 ACRYLIC PHOTOCURABLE COMPOSITION Changzhou Tronly Advanced Electronics Materials Co., Ltd. (CN) 2016-04-06 EP disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed