Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.52 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.52 |
| ▸ | KDR | P35968 | 3/20 | 0.51 |
| ▸ | BAZ1A | Q9NRL2 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | FLT3 | P36888 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL175205 | 0.88 | KDR (0.58) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL4569778 | 0.84 | MEN1 (0.53) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL174936 | 0.84 | MEN1 (0.51) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL174930 | 0.84 | RAB9A (0.52) | MAPTMEN1RAB9AKMT2ASTING1 | |
| SCHEMBL173797 | 0.82 | MEN1 (0.54) | MEN1RAB9AKMT2ATRPV1 | |
| SCHEMBL175067 | 0.81 | MAPT (0.52) | MAPTMEN1HTTRAB9AKMT2A | |
| SCHEMBL175262 | 0.81 | SMN1; SMN2 (0.55) | MAPTMEN1RAB9AKMT2AABCG2 | |
| SCHEMBL6670740 | 0.78 | NTRK1 (0.47) | HTTKMT2AKDR | |
| SCHEMBL174986 | 0.77 | KMT2A (0.52) | MAPTMEN1RAB9AKMT2ATRPV1 | |
| SCHEMBL173846 | 0.77 | STING1 (0.53) | MAPTMEN1HTTRAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2611806-A1 | DEUTERIUM-ENRICHED HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Ascepion Pharmaceuticals, Inc. (CN) | 2013-07-10 | — | — | EP | claimed |
| WO-2012028106-A1 | DEUTERIUM-ENRICHED HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ASCEPION PHARMACEUTICALS, INC. (CN) | 2012-03-08 | — | — | WO | claimed |
| EP-2611806-A1 | DEUTERIUM-ENRICHED HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | Ascepion Pharmaceuticals, Inc. (CN) | 2013-07-10 | — | — | EP | disclosed |
| WO-2012028106-A1 | DEUTERIUM-ENRICHED HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | ASCEPION PHARMACEUTICALS, INC. (CN) | 2012-03-08 | — | — | WO | disclosed |