SCHEMBL1754342

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18475740	0.83	TRPV1 (0.49)	TRPV1TAAR1HTR2AHTR2CCYP3A4
	SCHEMBL12629209	0.79	TAAR1 (0.46)	TAAR1TSHRMAPK1LMNANFKB1
	SCHEMBL5351939	0.79	TAAR1 (0.62)	TAAR1HTR2AHTR2CTSHRMAPK1
	SCHEMBL2908281	0.79	HMGCR (0.50)	TAAR1TSHRMAPK1LMNANFKB1
	SCHEMBL1753781	0.78	TRPV1 (0.48)	TRPV1TAAR1TSHRMAPK1LMNA
	SCHEMBL12629556	0.78	TRPV1 (0.48)	TRPV1TAAR1HTR2AHTR2CTSHR
	SCHEMBL13225464	0.78	TAAR1 (0.50)	TRPV1TAAR1TSHRMAPK1LMNA
	SCHEMBL5099200	0.77	GAA (0.53)	TRPV1TSHRNFKB1CYP3A4HMGCR
	Hydrochloric Acid SCHEMBL2007942	0.76	TRPV1 (0.47)	TRPV1TAAR1HTR2AHTR2CTSHR
	Hydrochloric Acid SCHEMBL2007605	0.76	TRPV1 (0.47)	TRPV1TAAR1TSHRMAPK1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.