Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24385282 | 0.88 | CASP1 (0.36) | CASP1CASP7HSD17B10MAPTKDM4E | |
| SCHEMBL31503035 | 0.83 | CA9 (0.35) | CASP1CASP7HSD17B10MAPTKDM4E | |
| SCHEMBL7650098 | 0.83 | CA9 (0.35) | CASP1CASP7HSD17B10MAPTKDM4E | |
| SCHEMBL19048949 | 0.80 | ALDH1A1 (0.42) | CASP1CASP7HSD17B10MAPTKDM4E | |
| SCHEMBL12128915 | 0.80 | ALDH1A1 (0.42) | CASP1CASP7HSD17B10MAPTKDM4E | |
| SCHEMBL7856986 | 0.78 | MAPT (0.36) | CASP1CASP7HSD17B10MAPTKDM4E | |
| SCHEMBL6847406 | 0.78 | CASP1 (0.41) | CASP1CASP7HSD17B10MAPTKDM4E | |
| SCHEMBL14304189 | 0.76 | TAAR1 (0.39) | HSD17B10MAPTKDM4ELMNAALDH1A1 | |
| SCHEMBL24116099 | 0.76 | GRIN2B (0.45) | CASP1CASP7HSD17B10MAPTKDM4E | |
| SCHEMBL7676238 | 0.75 | FFAR4 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118005598-A | High-stability high-brightness rhodamine derivative, preparation method and application thereof in near-infrared biological imaging | 西北工业大学宁波研究院 | 2024-05-10 | — | — | CN | claimed |
| CN-118005598-A | High-stability high-brightness rhodamine derivative, preparation method and application thereof in near-infrared biological imaging | 西北工业大学宁波研究院 | 2024-05-10 | — | — | CN | disclosed |
| WO-2022155419-A1 | INDAZOLES AND AZAINDAZOLES AS LRRK2 INHIBITORS | ESCAPE Bio, Inc. (US) | 2022-07-21 | — | — | WO | disclosed |
| WO-2021107736-A1 | ORGANIC LIGHT-EMITTING ELEMENT | 주식회사 엘지화학 | 2021-06-03 | — | — | WO | disclosed |
| WO-2021107737-A1 | ORGANIC LIGHT-EMITTING ELEMENT | 주식회사 엘지화학 | 2021-06-03 | — | — | WO | disclosed |
| WO-2021049889-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME | 주식회사 엘지화학 | 2021-03-18 | — | — | WO | disclosed |
| EP-3772517-A1 | ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING SAME, AND DIAGNOSTIC COMPOSITION INCLUDING SAME | Samsung Electronics Co., Ltd. (KR) | 2021-02-10 | — | — | EP | disclosed |
| EP-2874987-B1 | alpha-AND gamma-TRUXILLIC ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF | UNIV NEW YORK STATE RES FOUND (US) | 2020-03-25 | — | — | EP | disclosed |
| CN-108602780-A | New compound and its pharmacologically acceptable salt | 明治制果药业株式会社 | 2018-09-28 | — | — | CN | disclosed |
| EP-3301097-A2 | [1]BENZOTHIENO[3',2':4,5]IMIDAZO[1,2-A]PYRIDINE DERIVATIVES AND RELATED COMPOUNDS FOR USE IN ORGANIC LIGHT-EMITTING DEVICES (OLEDS) | Samsung Display Co., Ltd. (KR) | 2018-04-04 | — | — | EP | disclosed |
| CN-107793363-A | A kind of substituted aromatic amines base heteroaromatic class compound and its application as antineoplastic | 上海医药工业研究院 | 2018-03-13 | — | — | CN | disclosed |
| CN-105026362-B | Dicyclic compound | 百时美施贵宝公司 | 2017-07-14 | — | — | CN | disclosed |
| EP-3185868-A1 | NOVEL ULK1 INHIBITORS AND METHODS USING SAME | Salk Institute for Biological Studies (US) | 2017-07-05 | — | — | EP | disclosed |
| EP-3112369-A1 | FUSED PYRAZOLE DERIVATIVE HAVING AUTOTAXIN INHIBITORY ACTIVITY | The University of Tokyo (JP) | 2017-01-04 | — | — | EP | disclosed |
| WO-2016033100-A1 | NOVEL ULK1 INHIBITORS AND METHODS USING SAME | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2016-03-03 | — | — | WO | disclosed |