Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA5A | P35218 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.41 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5140207 | 0.82 | NR3C2 (0.44) | CA1CA2CA5ACA9KCNN4 | |
| SCHEMBL28043685 | 0.80 | MAPT (0.47) | CA1CA2CA5ACA9KCNN4 | |
| SCHEMBL17258983 | 0.79 | CA1 (0.56) | CA1CA2CA5ACA9KCNN4 | |
| SCHEMBL4204972 | 0.79 | CA2 (0.56) | CA1CA2CA5ACA9KCNN4 | |
| SCHEMBL15462549 | 0.75 | CA1 (0.47) | CA1CA2CA5ACA9KCNN4 | |
| SCHEMBL27704938 | 0.73 | CA2 (0.60) | CA1CA2CA5ACA9KCNN4 | |
| SCHEMBL6241031 | 0.73 | CA2 (0.60) | CA1CA2CA5ACA9KCNN4 | |
| Sulfuric Acid SCHEMBL29215267 | 0.73 | MAPT (0.48) | CA1CA2CA5ACA9KCNN4 | |
| SCHEMBL28638327 | 0.72 | CYP1A2 (0.44) | CA1CA2CA5ACA9KCNN4 | |
| SCHEMBL14486737 | 0.72 | L3MBTL1 (0.40) | CA1CA2CA5ACA9MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3186232-A1 | P38 MAP KINASE INHIBITING INDANYL UREA COMPOUNDS | Torrent Pharmaceuticals Limited (IN) | 2017-07-05 | — | — | EP | claimed |
| WO-2016030852-A1 | P38 MAP KINASE INHIBITING INDANYL UREA COMPOUNDS | TORRENT PHARMACEUTICALS LIMITED (IN) | 2016-03-03 | — | — | WO | claimed |