Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23888913 | 0.73 | PNMT (0.32) | — | |
| SCHEMBL17493552 | 0.67 | PNMT (0.38) | — | |
| SCHEMBL15825529 | 0.64 | PNMT (0.46) | — | |
| SCHEMBL19203254 | 0.64 | PNMT (0.46) | — | |
| SCHEMBL23877924 | 0.62 | FAAH (0.32) | — | |
| SCHEMBL17493533 | 0.62 | FAAH (0.39) | — | |
| SCHEMBL11051376 | 0.61 | CYP19A1 (0.35) | — | |
| Ammonia Solution, Strong SCHEMBL28234423 | 0.58 | CYP19A1 (0.33) | — | |
| SCHEMBL8848387 | 0.58 | CYP19A1 (0.32) | — | |
| SCHEMBL6891271 | 0.58 | CYP19A1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016022448-A1 | ANTIDIABETIC BICYCLIC COMPOUNDS | MERCK SHARP & DOHME CORP. (US) | 2016-02-11 | — | — | WO | disclosed |