SCHEMBL17545815

SCHEMBL17545815

N#Cc1ccc(Sc2ccc(C(=O)/C(CCC3CCCCC3)=N/OC(=O)c3ccccc3)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
LMNA P02545 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
TDP1 Q9NUW8 1/20 0.35
ALDH1A1 P00352 2/20 0.35
MAPT P10636 2/20 0.35
KDM4E B2RXH2 1/20 0.34
PKM P14618 1/20 0.34
ATM Q13315 1/20 0.34
CHRM4 P08173 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17070003 0.91 L3MBTL1 (0.43) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL17540444 0.91 L3MBTL1 (0.43) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL17070001 0.90 L3MBTL1 (0.44) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL19795438 0.90 L3MBTL1 (0.44) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL25373230 0.90 L3MBTL1 (0.44) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL17540464 0.88 KMT2A (0.50) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL17545816 0.86 SMN1; SMN2 (0.38) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL19795424 0.84 L3MBTL1 (0.40) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL17540462 0.84 MAPT (0.53) KMT2AMEN1SMN1; SMN2NPC1RAB9A
SCHEMBL17540459 0.83 KMT2A (0.39) KMT2AMEN1SMN1; SMN2NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
EP-3002632-A1 ACRYLIC PHOTOCURABLE COMPOSITION Changzhou Tronly Advanced Electronics Materials Co., Ltd. (CN) 2016-04-06 EP disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed