SCHEMBL17545816

SCHEMBL17545816

O=C(O/N=C(\CCC1CCCCC1)C(=O)c1ccc(Sc2ccc(C(F)(F)F)cc2)cc1)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
LMNA P02545 1/20 0.38
TNF P01375 1/20 0.36
KLF5 Q13887 1/20 0.36
NOD1 Q9Y239 1/20 0.36
MGLL Q99685 1/20 0.36
CYP3A4 P08684 2/20 0.36
HTT P42858 1/20 0.36
RECQL P46063 1/20 0.36
MAPT P10636 5/20 0.36
TDP1 Q9NUW8 1/20 0.36
ALDH1A1 P00352 2/20 0.36
KDM4E B2RXH2 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17540444 0.92 L3MBTL1 (0.43) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL17070003 0.92 L3MBTL1 (0.43) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL19795438 0.91 L3MBTL1 (0.44) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL17070001 0.91 L3MBTL1 (0.44) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL25373230 0.91 L3MBTL1 (0.44) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL17540464 0.89 KMT2A (0.50) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL17545815 0.86 KMT2A (0.37) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL19795424 0.85 L3MBTL1 (0.40) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL17540462 0.85 MAPT (0.53) SMN1; SMN2MEN1KMT2ANPC1RAB9A
SCHEMBL17540463 0.85 HPGDS (0.40) SMN1; SMN2MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3002632-B1 ACRYLIC PHOTOCURABLE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONICS MAT CO LTD (CN) 2018-03-28 EP disclosed
US-9383480-B2 Photocurable acrylate composition CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-07-05 US disclosed
EP-3002632-A1 ACRYLIC PHOTOCURABLE COMPOSITION Changzhou Tronly Advanced Electronics Materials Co., Ltd. (CN) 2016-04-06 EP disclosed
US-20160047945-A1 PHOTOCURABLE ACRYLATE COMPOSITION CHANGZHOU TRONLY ADVANCED ELECTRONIC MATERIALS CO., LTD. (CN) 2016-02-18 US disclosed