SCHEMBL17545909

SCHEMBL17545909

CC(C)(C)c1cc(-n2nc3ccc(S)cc3n2)c(O)c(C(C)(C)C)c1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 2/20 0.35
RAB9A P51151 2/20 0.35
HSP90AA1 P07900 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
TSHR P16473 1/20 0.34
CYP2C19 P33261 1/20 0.34
ALOX5 P09917 4/20 0.33
PTGS2 P35354 4/20 0.33
POLB P06746 2/20 0.32
LMNA P02545 1/20 0.32
CA2 P00918 2/20 0.31
CA1 P00915 1/20 0.31
ALDH1A1 P00352 2/20 0.30
GAA P10253 1/20 0.30
XBP1 P17861 1/20 0.30
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL712969 0.88 NPC1 (0.38) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL29706577 0.88 NPC1 (0.38) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL17545934 0.87 NPC1 (0.47) NPC1RAB9ACYP1A2CYP2C9CYP2C19
SCHEMBL22080465 0.86 NPC1 (0.37) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL24236671 0.85 NPC1 (0.36) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL24236672 0.85 NPC1 (0.36) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL6904762 0.85 NPC1 (0.44) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL29350736 0.85 NPC1 (0.49) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL29708 0.85 NPC1 (0.49) NPC1RAB9AHSP90AA1CYP1A2CYP3A4
SCHEMBL24205703 0.85 CA1 (0.42) NPC1RAB9AHSP90AA1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370780-B2 Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same MIYOSHI OIL & FAT CO., LTD. (JP) 2022-06-28 US disclosed
US-11186568-B2 Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same MIYOSHI OIL & FAT CO., LTD. (JP) 2021-11-30 US disclosed
US-20190315722-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME MIYOSHI OIL & FAT CO., LTD. (JP) 2019-10-17 US disclosed
US-20190248766-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME MIYOSHI OIL & FAT CO., LTD. (JP) 2019-08-15 US disclosed
US-10316024-B2 Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same MIYOSHI OIL & FAT CO., LTD. (JP) 2019-06-11 US disclosed
US-20170217937-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME MIYOSHI OIL & FAT CO., LTD. (JP) 2017-08-03 US disclosed
EP-3178898-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORPTIVITY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME Miyoshi Oil & Fat Co., Ltd. (JP) 2017-06-14 EP disclosed
WO-2016021664-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORPTIVITY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME ミヨシ油脂株式会社 2016-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170217937-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME INTS9, MMS19, F12 NPC1 3986/4885RAB9A 174/4885HSP90AA1 348/4885
US-20190315722-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME MMS19, INTS9, SRRM2 NPC1 4079/4885RAB9A 496/4885HSP90AA1 442/4885
US-10316024-B2 Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same INTS9, MMS19, F12 NPC1 3986/4885RAB9A 174/4885HSP90AA1 348/4885
US-11186568-B2 Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same MMS19, INTS9, SRRM2 NPC1 4079/4885RAB9A 496/4885HSP90AA1 442/4885
US-11370780-B2 Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same MMS19, INTS9, SRRM2 NPC1 4079/4885RAB9A 496/4885HSP90AA1 442/4885
US-20190248766-A1 ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME MMS19, INTS9, SRRM2 NPC1 4079/4885RAB9A 496/4885HSP90AA1 442/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.