Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549469 | 0.88 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL17545909 | 0.87 | NPC1 (0.35) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL880931 | 0.86 | NPC1 (0.49) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL29365942 | 0.85 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL208288 | 0.85 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| Bumetrizole SCHEMBL8603228 | 0.84 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| Bumetrizole SCHEMBL23734 | 0.84 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL22606047 | 0.84 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| SCHEMBL22589019 | 0.84 | NPC1 (0.50) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 | |
| Bumetrizole SCHEMBL8054070 | 0.84 | NPC1 (0.53) | NPC1RAB9ASMN1; SMN2POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11370780-B2 | Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same | MIYOSHI OIL & FAT CO., LTD. (JP) | 2022-06-28 | — | — | US | disclosed |
| US-11186568-B2 | Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same | MIYOSHI OIL & FAT CO., LTD. (JP) | 2021-11-30 | — | — | US | disclosed |
| US-20190315722-A1 | ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME | MIYOSHI OIL & FAT CO., LTD. (JP) | 2019-10-17 | — | — | US | disclosed |
| US-20190248766-A1 | ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME | MIYOSHI OIL & FAT CO., LTD. (JP) | 2019-08-15 | — | — | US | disclosed |
| US-10316024-B2 | Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same | MIYOSHI OIL & FAT CO., LTD. (JP) | 2019-06-11 | — | — | US | disclosed |
| US-20170217937-A1 | ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME | MIYOSHI OIL & FAT CO., LTD. (JP) | 2017-08-03 | — | — | US | disclosed |
| EP-3178898-A1 | ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORPTIVITY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME | Miyoshi Oil & Fat Co., Ltd. (JP) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016174788-A1 | PLASTIC LENS | 東海光学株式会社 | 2016-11-03 | — | — | WO | disclosed |
| WO-2016021664-A1 | ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORPTIVITY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME | ミヨシ油脂株式会社 | 2016-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170217937-A1 | ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME | INTS9, MMS19, F12 | NPC1 3986/4885RAB9A 174/4885SMN1; SMN2 1682/4885 |
| US-20190315722-A1 | ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME | MMS19, INTS9, SRRM2 | NPC1 4079/4885RAB9A 496/4885SMN1; SMN2 928/4885 |
| US-10316024-B2 | Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same | INTS9, MMS19, F12 | NPC1 3986/4885RAB9A 174/4885SMN1; SMN2 1682/4885 |
| US-11186568-B2 | Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same | MMS19, INTS9, SRRM2 | NPC1 4079/4885RAB9A 496/4885SMN1; SMN2 928/4885 |
| US-11370780-B2 | Additive for imparting ultraviolet absorbency and/or high refractive index to matrix, and resin member using same | MMS19, INTS9, SRRM2 | NPC1 4079/4885RAB9A 496/4885SMN1; SMN2 928/4885 |
| US-20190248766-A1 | ADDITIVE FOR IMPARTING ULTRAVIOLET ABSORBENCY AND/OR HIGH REFRACTIVE INDEX TO MATRIX, AND RESIN MEMBER USING SAME | MMS19, INTS9, SRRM2 | NPC1 4079/4885RAB9A 496/4885SMN1; SMN2 928/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.