Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.34 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | CFD | P00746 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9607776 | 0.91 | ERN1 (0.40) | ERN1THRBTHRATYMSMAPK1 | |
| SCHEMBL16803332 | 0.88 | MAPT (0.42) | ERN1THRBTHRATYMSMAPK1 | |
| SCHEMBL18808272 | 0.87 | ERN1 (0.51) | ERN1PTGS2PTGS1MAPK1FFAR1 | |
| SCHEMBL20312065 | 0.85 | ERN1 (0.50) | ERN1PTGS2PTGS1MAPK1FFAR1 | |
| SCHEMBL15908400 | 0.85 | THRB (0.46) | THRBTHRATYMSPPARGPPARA | |
| SCHEMBL2604655 | 0.85 | TYMS (0.41) | ERN1THRBTHRAHSD17B1HSD17B2 | |
| SCHEMBL9613625 | 0.85 | THRB (0.43) | ERN1THRBTHRATYMSMAPK1 | |
| SCHEMBL18194804 | 0.84 | ERN1 (0.37) | ERN1THRBTHRATYMSMAPK1 | |
| SCHEMBL2604656 | 0.84 | ERN1 (0.39) | ERN1THRBTHRATYMSMAPK1 | |
| SCHEMBL16488179 | 0.84 | KDM4E (0.47) | ERN1HSD17B1HSD17B2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3112440-A1 | LIQUID-CRYSTAL MEDIUM | Merck Patent GmbH (DE) | 2017-01-04 | — | — | EP | disclosed |
| EP-2990460-A1 | LIQUID CRYSTALLINE MEDIUM | Merck Patent GmbH (DE) | 2016-03-02 | — | — | EP | disclosed |