Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.51 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27432172 | 0.94 | TAAR1 (0.56) | POLBALDH1A1MAPTKMT2AGAA | |
| SCHEMBL7978304 | 0.82 | KLK7 (0.61) | POLBALDH1A1MAPTKMT2AGAA | |
| SCHEMBL8927647 | 0.82 | POLB (0.53) | POLBALDH1A1MAPTKMT2AGAA | |
| SCHEMBL9515695 | 0.81 | MAPT (0.56) | POLBALDH1A1MAPTKMT2AGAA | |
| SCHEMBL8927298 | 0.81 | ALDH1A1 (0.61) | POLBALDH1A1MAPTKMT2AGAA | |
| SCHEMBL6973912 | 0.81 | POLB (0.52) | POLBALDH1A1MAPTKMT2AGAA | |
| SCHEMBL8049390 | 0.81 | ALDH1A1 (0.77) | POLBALDH1A1MAPTKMT2AGAA | |
| SCHEMBL16713399 | 0.79 | KLK7 (0.57) | POLBALDH1A1MAPTKMT2AGAA | |
| SCHEMBL587395 | 0.79 | MAPT (0.59) | POLBALDH1A1MAPTKMT2AGAA | |
| SCHEMBL27799414 | 0.79 | KMT2A (0.56) | ALDH1A1MAPTKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1831153-A2 | COMPOUNDS DERIVED FROM LIDOCAINE, PHARMACEUTICAL COMPOSITIONS, USE AND METHOD OF TREATMENT, PREVENTION OR INHIBITION OF DISEASES | FUNDA AO OSWALDO CRUZ-FIOCRUZ (BR) | 2007-09-12 | — | — | EP | claimed |
| CN-1989099-A | Compounds derived from lidocaine, pharmaceutical compositions, use and method of treatment, prevention or inhibition of diseases | FUNDACAO OSWALDO CRUZ (BR) | 2007-06-27 | — | — | CN | claimed |
| WO-2005120148-A2 | COMPOUNDS DERIVED FROM LIDOCAINE, PHARMACEUTICAL COMPOSITIONS, USE AND METHOD OF TREATMENT, PREVENTION OR INHIBITION OF DISEASES | FUNDAÇÃO OSWALDO CRUZ-FIOCRUZ (BR) | 2005-12-22 | — | — | WO | claimed |
| CN-113474156-B | Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same | 东丽株式会社 | 2022-04-29 | — | — | CN | disclosed |
| CN-113474156-A | Polyamic acid resin composition, polyimide resin film and method for producing same, laminate, and electronic device and method for producing same | 东丽株式会社 | 2021-10-01 | — | — | CN | disclosed |
| CN-1989099-B | Compounds derived from lidocaine, pharmaceutical compositions, use and method of treatment, prevention or inhibition of diseases | FUNDACAO OSWALDO CRUZ | 2013-10-30 | — | — | CN | disclosed |
| EP-1831153-A2 | COMPOUNDS DERIVED FROM LIDOCAINE, PHARMACEUTICAL COMPOSITIONS, USE AND METHOD OF TREATMENT, PREVENTION OR INHIBITION OF DISEASES | FUNDA AO OSWALDO CRUZ-FIOCRUZ (BR) | 2007-09-12 | — | — | EP | disclosed |
| CN-1989099-A | Compounds derived from lidocaine, pharmaceutical compositions, use and method of treatment, prevention or inhibition of diseases | FUNDACAO OSWALDO CRUZ (BR) | 2007-06-27 | — | — | CN | disclosed |
| WO-2005120148-A2 | COMPOUNDS DERIVED FROM LIDOCAINE, PHARMACEUTICAL COMPOSITIONS, USE AND METHOD OF TREATMENT, PREVENTION OR INHIBITION OF DISEASES | FUNDAÇÃO OSWALDO CRUZ-FIOCRUZ (BR) | 2005-12-22 | — | — | WO | disclosed |