SCHEMBL587395

SCHEMBL587395

COC(C(C)=O)C(=O)Nc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.59
ALDH1A1 P00352 4/20 0.59
GAA P10253 2/20 0.59
LMNA P02545 1/20 0.59
ATM Q13315 1/20 0.59
NAPRT Q6XQN6 1/20 0.52
HSD17B10 Q99714 1/20 0.52
KMT2A Q03164 5/20 0.50
POLB P06746 3/20 0.50
MEN1 O00255 3/20 0.50
RXFP1 Q9HBX9 1/20 0.50
CYP1A2 P05177 1/20 0.49
CYP2C19 P33261 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
MME P08473 1/20 0.47
ACE P12821 1/20 0.47
HSP90AA1 P07900 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
HDAC2 Q92769 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9515695 0.87 MAPT (0.56) MAPTALDH1A1GAALMNAATM
SCHEMBL11063197 0.85 MAPT (0.44) MAPTALDH1A1GAALMNAATM
SCHEMBL11062799 0.84 KMT2A (0.55) ALDH1A1LMNAKMT2APOLBMEN1
SCHEMBL8641268 0.83 GAA (0.58) MAPTALDH1A1GAALMNAATM
SCHEMBL11380977 0.83 ALDH1A1 (0.56) MAPTALDH1A1GAALMNAATM
SCHEMBL5928883 0.82 HSD17B10 (0.58) MAPTALDH1A1HSD17B10KMT2APOLB
SCHEMBL11133957 0.82 ALDH1A1 (0.48) MAPTALDH1A1GAALMNAATM
SCHEMBL11382012 0.81 MAPT (0.54) MAPTALDH1A1GAALMNAATM
SCHEMBL1255273 0.81 ALDH1A1 (0.60) MAPTALDH1A1KMT2APOLBRXFP1
SCHEMBL8752430 0.81 HPGD (0.55) MAPTALDH1A1LMNAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 73 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114736532-A High-speed high-tinting-strength and peculiar-smell-free pigment yellow synthesis method 浙江科隆颜料科技有限公司 2022-07-12 CN claimed
CN-111921465-B Azo pigment continuous synthesis micro mixer and continuous preparation method thereof 天津大学 2022-02-01 CN claimed
CN-109971211-B Pigment composition 山阳色素株式会社 2021-11-30 CN claimed
CN-111921465-A Azo pigment continuous synthesis micro mixer and continuous preparation method thereof 天津大学 2020-11-13 CN claimed
CN-110787747-B Tubular micro mixer and continuous preparation method of azo pigment by using same 天津大学 2020-09-29 CN claimed
CN-110787747-A Tubular micro mixer and continuous preparation method of azo pigment by using same 天津大学 2020-02-14 CN claimed
US-6692559-B2 MONOAZO DYES TOYO INK MANUFACTURING COMPANY (JP) 2004-02-17 US claimed
US-20030140819-A1 Pigment yellow 74 and printing ink composition TOYO INK MANUFACTURING COMPANY (JP) 2003-07-31 US claimed
EP-1316588-A2 Pigment yellow 74 and printing ink composition TOYO INK MANUFACTURING CO., LTD. (JP) 2003-06-04 EP claimed
US-4054585-A FUNGICIDES, INSECTICIDES UNIROYAL, INC. (US) 1977-10-18 US claimed
CN-115584071-A Preparation method of HDPE (high-density polyethylene) antibacterial plastic 周紫璇 2023-01-10 CN disclosed
US-11549018-B2 Pigment composition SANYO COLOR WORKS, LTD. (JP) 2023-01-10 US disclosed
CN-114736532-A High-speed high-tinting-strength and peculiar-smell-free pigment yellow synthesis method 浙江科隆颜料科技有限公司 2022-07-12 CN disclosed
CN-112662195-B Storage-stable organic yellow pigment and preparation method thereof 杭州百合科莱恩颜料有限公司 2022-05-31 CN disclosed
CN-111849195-B Production method of low-PCBs high-tinting-strength yellow pigment for plastics 浙江科隆颜料科技有限公司 2022-03-08 CN disclosed
US-5731422-A DYEING PLASTICS, LACQUERS CLARIANT FINANCE (BVI) LIMITED (VG) 1998-03-24 US disclosed
WO-1997043344-A1 MIXTURES OF 2:1 ALUMINIUM COMPLEXES CLARIANT FINANCE (BVI) LIMITED (VG) 1997-11-20 WO disclosed
US-4957847-A THERMAL PRINTING CIBA-GEIGY CORPORATION (US) 1990-09-18 US disclosed
US-4732975-A ORGANIC PIGMENTS HOECHST AKTIENGESELLSCHAFT (DE) 1988-03-22 US disclosed
EP-0034725-A2 Dyestuffs containing imidazolylethylene groups and their use BASF Aktiengesellschaft (DE) 1981-09-02 EP disclosed