Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | NPY1R | P25929 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPY2R | P49146 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17549849 | 1.00 | ADORA3 (0.46) | ADORA3ADORA2AADORA1ADORA2BLMNA | |
| SCHEMBL18949853 | 1.00 | ADORA3 (0.46) | ADORA3ADORA2AADORA1ADORA2BLMNA | |
| SCHEMBL8937131 | 0.83 | ADORA3 (0.46) | ADORA3ADORA2AADORA1ADORA2BPRMT6 | |
| SCHEMBL31154630 | 0.80 | ADORA3 (0.71) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL17099315 | 0.80 | ADORA3 (0.71) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL6746488 | 0.80 | ADORA3 (0.56) | ADORA3ADORA2AADORA1ADORA2BLMNA | |
| SCHEMBL17109605 | 0.80 | ADORA3 (0.71) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL17099316 | 0.80 | ADORA3 (0.71) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL1068380 | 0.80 | ADORA3 (0.43) | ADORA3ADORA2AADORA1ADORA2BPRMT6 | |
| SCHEMBL22915811 | 0.80 | ADORA1 (0.46) | ADORA3ADORA2AADORA1ADORA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016033164-A1 | NUCLEOSIDE AND NUCLEOTIDE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2016-03-03 | — | — | WO | disclosed |