Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1068380 | 0.91 | ADORA3 (0.43) | ADORA3ADORA2AADORA1PRMT6ADORA2B | |
| SCHEMBL31260592 | 0.85 | ADORA3 (0.55) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL9293858 | 0.84 | ADORA1 (0.44) | ADORA3ADORA2AADORA1PRMT6ADORA2B | |
| SCHEMBL17548588 | 0.83 | ADORA3 (0.46) | ADORA3ADORA2AADORA1PRMT6ADORA2B | |
| SCHEMBL18949853 | 0.83 | ADORA3 (0.46) | ADORA3ADORA2AADORA1PRMT6ADORA2B | |
| SCHEMBL17549849 | 0.83 | ADORA3 (0.46) | ADORA3ADORA2AADORA1PRMT6ADORA2B | |
| SCHEMBL17549848 | 0.80 | ADORA3 (0.41) | ADORA3ADORA2AADORA1PRMT6ADORA2B | |
| SCHEMBL17109605 | 0.80 | ADORA3 (0.71) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL31154630 | 0.80 | ADORA3 (0.71) | ADORA3ADORA2AADORA1ADORA2B | |
| SCHEMBL17099315 | 0.80 | ADORA3 (0.71) | ADORA3ADORA2AADORA1ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556840-A | 2',5'-phosphorothioate oligoadenylates as anitiviral agents | TEMPLE UNIVERSITY - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1996-09-17 | — | — | US | disclosed |
| US-5405939-A | viricides | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1995-04-11 | — | — | US | disclosed |
| US-5188897-A | Viricides, metabolic stability | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1993-02-23 | — | — | US | disclosed |
| EP-0389521-A4 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | — | 1992-02-05 | — | — | EP | disclosed |
| US-4924624-A | TOBACCO MOSAIC VIRUS | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 1990-05-15 | — | — | US | disclosed |
| WO-1989003683-A1 | 2',5'-PHOSPHOROTHIOATE OLIGOADENYLATES AND ANTIVIRAL USES THEREOF | TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HI (US) | 1989-05-05 | — | — | WO | disclosed |