SCHEMBL17548764

SCHEMBL17548764

Oc1cc(O)c2c(c1)OC1(c3cc(O)c(O)c(O)c3)Oc3cc(O)c4c(c3C2C1O)OC(c1cc(O)c(O)c(O)c1)C(O)C4

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
VEGFA P15692 3/20 0.78
PGF P49763 3/20 0.78
PRKAA2 P54646 1/20 0.78
FLT1 P17948 2/20 0.74
PRKD3 O94806 3/20 0.70
PRKCG P05129 3/20 0.70
PRKCB P05771 3/20 0.70
PRKCA P17252 3/20 0.70
PRKCH P24723 3/20 0.70
PRKCI P41743 3/20 0.70
PRKCE Q02156 3/20 0.70
PRKCQ Q04759 3/20 0.70
PRKCZ Q05513 3/20 0.70
PRKCD Q05655 3/20 0.70
PRKD1 Q15139 3/20 0.70
PDE4D Q08499 1/20 0.61
SNCA P37840 4/20 0.56
BACE1 P56817 2/20 0.56
ALOX15 P16050 2/20 0.56
HSD17B10 Q99714 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1689431 0.94 VEGFA (0.90) VEGFAPGFPRKAA2FLT1PRKD3
SCHEMBL13979111 0.90 VEGFA (0.65) VEGFAPGFPRKAA2FLT1PRKD3
SCHEMBL14598141 0.88 VEGFA (0.62) VEGFAPGFPRKAA2FLT1PRKD3
Proanthocyanidin A2 SCHEMBL981582 0.88 VEGFA (1.00) VEGFAPGFPRKAA2FLT1PRKD3
Proanthocyanidin A2 SCHEMBL18214185 0.88 VEGFA (1.00) VEGFAPGFPRKAA2FLT1PRKD3
Proanthocyanidin A2 SCHEMBL18350173 0.88 VEGFA (1.00) VEGFAPGFPRKAA2FLT1PRKD3
Proanthocyanidin A1 SCHEMBL1689429 0.88 VEGFA (1.00) VEGFAPGFPRKAA2FLT1PRKD3
Proanthocyanidin A2 SCHEMBL15398842 0.88 VEGFA (1.00) VEGFAPGFPRKAA2FLT1PRKD3
Proanthocyanidin A2 SCHEMBL13285132 0.88 VEGFA (1.00) VEGFAPGFPRKAA2FLT1PRKD3
Proanthocyanidin A2 SCHEMBL15394643 0.88 VEGFA (1.00) VEGFAPGFPRKAA2FLT1PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160058813-A1 Pea (Pisum sativum L.) Seed Coats and Seed Coat Fractions THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2016-03-03 US disclosed