SCHEMBL17548799

SCHEMBL17548799

COC[C@H](O)C(=O)Nc1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.53
ALDH1A1 P00352 5/20 0.53
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
RXFP1 Q9HBX9 1/20 0.53
HPGD P15428 2/20 0.53
HTT P42858 2/20 0.53
MAPK1 P28482 2/20 0.53
ALOX12 P18054 1/20 0.53
HDAC2 Q92769 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.49
LMNA P02545 1/20 0.49
GAA P10253 1/20 0.49
ATM Q13315 1/20 0.49
POLB P06746 1/20 0.49
MME P08473 1/20 0.46
ACE P12821 1/20 0.46
HSP90AA1 P07900 1/20 0.46
GPR55 Q9Y2T6 1/20 0.46
KLK7 P49862 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13345375 0.81 MEN1 (0.49) MAPTALDH1A1MEN1KMT2ARXFP1
SCHEMBL13345404 0.81 MEN1 (0.49) MAPTALDH1A1MEN1KMT2ARXFP1
SCHEMBL13345396 0.81 MEN1 (0.49) MAPTALDH1A1MEN1KMT2ARXFP1
SCHEMBL18199393 0.81 MEN1 (0.44) MAPTALDH1A1MEN1KMT2ARXFP1
SCHEMBL4594451 0.80 MEN1 (0.62) MAPTALDH1A1MEN1KMT2ARXFP1
SCHEMBL29245669 0.79 CA12 (0.65) MAPTALDH1A1MEN1KMT2ARXFP1
SCHEMBL28548192 0.78 POLB (0.55) MAPTALDH1A1MEN1KMT2ARXFP1
SCHEMBL10700016 0.78 MAPT (0.51) MAPTALDH1A1MEN1KMT2ARXFP1
SCHEMBL7561838 0.77 MAPT (0.49) MAPTALDH1A1MEN1KMT2ARXFP1
SCHEMBL26616888 0.77 MAPT (0.49) MAPTALDH1A1MEN1KMT2ARXFP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160060210-A1 Process for the Preparation of Lacosamide and Its Novel Intermediate RAO, Davuluri Ramamohan (IN) 2016-03-03 US disclosed
US-20160060210-A1 Process for the Preparation of Lacosamide and Its Novel Intermediate RAO, Davuluri Ramamohan (IN) 2016-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160060210-A1 Process for the Preparation of Lacosamide and Its Novel Intermediate SCN11A, CACNA1B, SLC6A11 MAPT 2535/4885ALDH1A1 1311/4885MEN1 3295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.