Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 6/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 7/20 | 0.43 |
| ▸ | FLT4 | P35916 | 7/20 | 0.43 |
| ▸ | KDR | P35968 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3059734 | 0.80 | SCN9A (0.43) | NPC1RAB9ASCN9AFLT1FLT4 | |
| SCHEMBL10515182 | 0.80 | POLB (0.49) | NPC1RAB9AGAAMAPTHTT | |
| SCHEMBL9878340 | 0.78 | KMT2A (0.53) | NPC1RAB9AALDH1A1MAPTPOLB | |
| SCHEMBL1014802 | 0.76 | TSHR (0.44) | NPC1RAB9AALDH1A1MAPTHTT | |
| SCHEMBL973982 | 0.76 | NPC1 (0.43) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL12494124 | 0.76 | HPGD (0.69) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL31468684 | 0.75 | CA12 (0.46) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL6586312 | 0.75 | CA12 (0.46) | NPC1RAB9AALDH1A1GAAMAPT | |
| SCHEMBL9419239 | 0.75 | NPC1 (0.42) | NPC1RAB9AALDH1A1GAAMAPT | |
| Hydrochloric Acid SCHEMBL3983490 | 0.75 | TSHR (0.42) | NPC1RAB9AALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2537829-B1 | Aminobenzoylsulfonamides and their preparation | BASF SE (DE) | 2016-03-02 | — | — | EP | disclosed |