Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.40 |
| ▸ | PPOX | P50336 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3983490 | 0.98 | TSHR (0.42) | TSHRNPC1RAB9ADTYMKTDP1 | |
| SCHEMBL7744994 | 0.93 | TSHR (0.44) | TSHRNPC1RAB9ADTYMKTDP1 | |
| Benzoic Acid SCHEMBL25317758 | 0.90 | VCAM1 (0.49) | TSHRNPC1RAB9ATDP1AKR1C2 | |
| SCHEMBL241760 | 0.86 | VCAM1 (0.45) | TSHRNPC1RAB9ADTYMKTDP1 | |
| SCHEMBL973982 | 0.86 | NPC1 (0.43) | TSHRNPC1RAB9ATDP1ATM | |
| SCHEMBL1790306 | 0.85 | TSHR (0.49) | TSHRDTYMKTDP1ALDH1A1VCAM1 | |
| SCHEMBL9419239 | 0.85 | NPC1 (0.42) | TSHRNPC1RAB9ATDP1ATM | |
| SCHEMBL9878340 | 0.85 | KMT2A (0.53) | NPC1RAB9ATDP1ATMALDH1A1 | |
| SCHEMBL6586312 | 0.85 | CA12 (0.46) | NPC1RAB9ATDP1ATMESPL1 | |
| SCHEMBL31468684 | 0.85 | CA12 (0.46) | NPC1RAB9ATDP1ATMESPL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 433 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260085051-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | ADAMA AGAN LTD. (IL) | 2026-03-26 | — | — | US | claimed |
| EP-4313954-B1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | ADAMA AGAN LTD (IL) | 2025-10-15 | — | — | EP | claimed |
| CN-119790033-A | Preparation of 2-chloro-4-fluoro-5-nitrobenzoic acid | 安道麦阿甘有限公司 | 2025-04-08 | — | — | CN | claimed |
| CN-119306610-A | Synthesis method of 2-chloro-4-fluoro-5-nitrobenzoic acid | 永农生物科学有限公司 | 2025-01-14 | — | — | CN | claimed |
| CN-114105772-B | Synthesis method of 2-chloro-4-fluoro-5-nitrobenzoic acid | 阜新睿光氟化学有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-118955293-A | Preparation method of 2-chloro-4-fluoro-5-nitrobenzoic acid | 北京颖泰嘉和生物科技股份有限公司 | 2024-11-15 | — | — | CN | claimed |
| US-20240217915-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | ADAMA AGAN LTD. (IL) | 2024-07-04 | — | — | US | claimed |
| WO-2024047648-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | ADAMA AGAN LTD. (IL) | 2024-03-07 | — | — | WO | claimed |
| EP-4313954-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | Adama Agan Ltd. (IL) | 2024-02-07 | — | — | EP | claimed |
| CN-117062805-A | Preparation of 2-chloro-4-fluoro-5-nitrobenzoic acid | 安道麦阿甘有限公司 | 2023-11-14 | — | — | CN | claimed |
| CN-112939922-B | Synthesis method of 1-cyano-6-methylsulfonyl-7-nitro-9H-xanthene-9-ketone | 龙曦宁（上海）医药科技有限公司 | 2023-02-24 | — | — | CN | claimed |
| CN-114105772-A | Synthetic method of 2-chloro-4-fluoro-5-nitrobenzoic acid | 阜新睿光氟化学有限公司 | 2022-03-01 | — | — | CN | claimed |
| CN-112939922-A | Synthesis method of 1-cyano-6-methylsulfonyl-7-nitro-9H-xanthene-9-ketone | 龙曦宁（上海）医药科技有限公司 | 2021-06-11 | — | — | CN | claimed |
| CN-101142168-B | Method for producing benzoic acid derivatives via novel synthesis intermediates | BASF AG | 2012-03-28 | — | — | CN | claimed |
| EP-1853548-B1 | PROCESS FOR THE PREPARATION OF BENZOIC ACID DERIVATIVES VIA A NEW INTERMEDIATE OF SYNTHESIS | MITENI SPA (IT) | 2009-05-13 | — | — | EP | claimed |
| CN-101142168-A | Method for producing benzoic acid derivatives via novel synthesis intermediates | MITENI SPA (DE) | 2008-03-12 | — | — | CN | claimed |
| EP-1853548-A1 | PROCESS FOR THE PREPARATION OF BENZOIC ACID DERIVATIVES VIA A NEW INTERMEDIATE OF SYNTHESIS | MITENI S.p.A. (IT) | 2007-11-14 | — | — | EP | claimed |
| WO-2006090210-A1 | PROCESS FOR THE PREPARATION OF BENZOIC ACID DERIVATIVES VIA A NEW INTERMEDIATE OF SYNTHESIS | MITENI S.P.A. (IT) | 2006-08-31 | — | — | WO | claimed |
| US-20260085051-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | ADAMA AGAN LTD. (IL) | 2026-03-26 | — | — | US | disclosed |
| EP-0061741-A2 | Tetrahydrophthalimides, and their production and use | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240217915-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | CYP4F12, COXFA4, NDUFS5 | TSHR 2171/4885NPC1 3580/4885RAB9A 3796/4885 |
| US-20260085051-A1 | PREPARATION OF 2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID | FOSB, DDT, NPM1 | TSHR 2588/4885NPC1 2561/4885RAB9A 2995/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.