Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.38 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.38 |
| ▸ | FKBP14 | Q9NWM8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6909012 | 0.76 | PIK3CD (0.30) | — | |
| SCHEMBL2349094 | 0.75 | SMN1; SMN2 (0.39) | SMN1; SMN2ALDH1A1FKBP1ALMNANPC1 | |
| SCHEMBL9565118 | 0.71 | TSHR (0.38) | SMN1; SMN2ALDH1A1FKBP1ALMNANPC1 | |
| SCHEMBL11940967 | 0.70 | EPHX2 (0.41) | SMN1; SMN2ALDH1A1FKBP1ALMNANPC1 | |
| SCHEMBL6906976 | 0.70 | CA1 (0.37) | TP53HTT | |
| SCHEMBL6907551 | 0.68 | TLR4 (0.47) | — | |
| SCHEMBL10700337 | 0.67 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1FKBP1ALMNANPC1 | |
| SCHEMBL13671685 | 0.65 | CA1 (0.42) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL14959244 | 0.64 | SMN1; SMN2 (0.33) | SMN1; SMN2ALDH1A1FKBP1ALMNANPC1 | |
| SCHEMBL18588303 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8158372-B2 | Agonists of a bitter taste receptor and uses thereof | DEUTSCHES INSTITUT FÜR ERNÄHRUNGSFORSCHUNG POTSDAM-REHBRÜCKE (DE) | 2012-04-17 | — | — | US | disclosed |