Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.33 |
| ▸ | FKBP4 | Q02790 | 2/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013962 | 0.77 | TSHR (0.38) | TSHRALDH1A1TDP1LMNAHTT | |
| SCHEMBL9014001 | 0.76 | TLR4 (0.45) | TSHRALDH1A1TDP1LMNASMN1; SMN2 | |
| SCHEMBL9014348 | 0.73 | TSHR (0.36) | TSHRALDH1A1TDP1LMNAHTT | |
| SCHEMBL22754195 | 0.73 | TSHR (0.43) | TSHRALDH1A1TDP1LMNAHTT | |
| SCHEMBL10614279 | 0.72 | TSHR (0.46) | TSHRALDH1A1TDP1LMNAHTT | |
| SCHEMBL1754902 | 0.71 | SMN1; SMN2 (0.38) | ALDH1A1FKBP1AFKBP4FKBP5LMNA | |
| SCHEMBL10848706 | 0.70 | TSHR (0.40) | TSHRALDH1A1TDP1LMNAHTT | |
| SCHEMBL22680909 | 0.70 | TSHR (0.33) | TSHRALDH1A1TDP1LMNAHTT | |
| SCHEMBL11763977 | 0.67 | NPC1 (0.54) | TSHRALDH1A1TDP1LMNAHTT | |
| SCHEMBL9511515 | 0.66 | TSHR (0.50) | TSHRALDH1A1TDP1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0551019-A1 | Catalytic process of producing coumarin and derivatives thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1993-07-14 | — | — | EP | disclosed |