Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | NR2F2 | P24468 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.54 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | EIF4A1 | P60842 | 1/20 | 0.54 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.54 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.54 |
| ▸ | FKBP14 | Q9NWM8 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28101646 | 0.79 | SMN1; SMN2 (0.43) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 | |
| SCHEMBL17616907 | 0.71 | SMN1; SMN2 (0.53) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 | |
| Cycloheximide SCHEMBL674135 | 0.70 | FKBP1A (1.00) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 | |
| Cycloheximide SCHEMBL1753509 | 0.70 | FKBP1A (1.00) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 | |
| Cycloheximide SCHEMBL3764340 | 0.70 | FKBP1A (1.00) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 | |
| Cycloheximide SCHEMBL24914327 | 0.70 | FKBP1A (1.00) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 | |
| Cycloheximide SCHEMBL9344504 | 0.70 | FKBP1A (1.00) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 | |
| Cycloheximide SCHEMBL26617 | 0.70 | FKBP1A (1.00) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 | |
| Cycloheximide SCHEMBL17223570 | 0.70 | FKBP1A (1.00) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 | |
| Cycloheximide SCHEMBL30020292 | 0.70 | FKBP1A (1.00) | SMN1; SMN2NR2F2LMNANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4766113-A | METAL CHELATE OF 8-HYDROXY QUINOLINE AND ALKYLOENZENE SULFONIC ACID | CHAPMAN CHEMICAL COMPANY (US) | 1988-08-23 | — | — | US | disclosed |
| US-4602011-A | METAL CHELATE OF 8-HYDROXY QUINOLINE AND AN ALKYL BENZENE SULFONIC ACID | CHAPMAN CHEMICAL COMPANY (US) | 1986-07-22 | — | — | US | disclosed |