Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | GLRA1 | P23415 | 2/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.36 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28110030 | 0.95 | TYR (0.37) | TYRALPIPKMPTGS1XIAP | |
| Trifluoroacetic Acid SCHEMBL17537149 | 0.95 | TYR (0.37) | TYRALPIPKMPTGS1XIAP | |
| SCHEMBL17549495 | 0.86 | LARS1 (0.33) | SOAT2SOAT1 | |
| SCHEMBL21154976 | 0.86 | LARS1 (0.33) | SOAT2SOAT1 | |
| Trifluoroacetic Acid SCHEMBL17537129 | 0.84 | DPP4 (0.33) | GLRA1DPP4 | |
| SCHEMBL17549493 | 0.83 | SCN5A (0.34) | SOAT2SOAT1 | |
| SCHEMBL17598365 | 0.81 | LMNA (0.37) | SOAT2SOAT1LMNATDP1 | |
| Trifluoroacetic Acid SCHEMBL17537151 | 0.81 | DPP4 (0.36) | GLRA1DPP4 | |
| SCHEMBL17549488 | 0.81 | SCN5A (0.35) | — | |
| SCHEMBL17549500 | 0.81 | DPP8 (0.35) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9517988-B2 | Phenol derivative and preparation method and use in medicine thereof | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-12-13 | — | — | US | disclosed |
| US-9517988-B2 | Phenol derivative and preparation method and use in medicine thereof | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-12-13 | — | — | US | disclosed |
| EP-2995604-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2016-03-16 | — | — | EP | disclosed |
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-03-03 | — | — | US | disclosed |
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | SICHUAN HAISCO PHARMACEUTICAL CO., LTD. (CN) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060197-A1 | PHENOL DERIVATIVE AND PREPARATION METHOD AND USE IN MEDICINE THEREOF | CYP2D6, CYP2B6, CYP2A6 | TYR 73/4885ALPI 311/4885PKM 300/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.