Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 10/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27811710 | 0.82 | HSD17B10 (0.73) | HSD17B10SLC6A3SLC6A2CYP2C9CYP2C19 | |
| Hydrochloric Acid SCHEMBL6048626 | 0.81 | HSD17B10 (0.71) | HSD17B10SLC6A3SLC6A2CYP2C9CYP2C19 | |
| SCHEMBL17549634 | 0.81 | HSD17B10 (0.52) | HSD17B10SLC6A3CYP2C9CYP2C19SLC6A4 | |
| SCHEMBL17549641 | 0.72 | HSD17B10 (0.52) | HSD17B10DRD3OPRD1HSP90AA1ALDH1A1 | |
| SCHEMBL17549636 | 0.71 | HPGD (0.52) | HSD17B10SLC6A3SLC6A2SLC6A4CHRM2 | |
| SCHEMBL9850531 | 0.71 | ALDH1A1 (0.55) | HSD17B10CYP2C9CYP2C19CHRM2CYP2D6 | |
| SCHEMBL15599303 | 0.71 | HSD17B10 (1.00) | HSD17B10CYP2C9CYP2C19DRD3CYP1A2 | |
| SCHEMBL11304836 | 0.70 | HPGD (0.47) | SLC6A3SLC6A2CYP2C9CYP2C19SLC6A4 | |
| SCHEMBL28034427 | 0.69 | ALDH1A1 (0.63) | CYP2C9CYP2C19HPGDMAPK1ALDH1A1 | |
| SCHEMBL13181405 | 0.69 | ALDH1A1 (0.68) | HSD17B10SLC6A3SLC6A2CYP2C9CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060235-A1 | Therapeutic Agent for Type 2 Diabetes | NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) | 2016-03-03 | — | — | US | disclosed |
| US-20160060235-A1 | Therapeutic Agent for Type 2 Diabetes | NATIONAL UNIVERSITY CORPORATION KUMAMOTO UNIVERSITY (JP) | 2016-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060235-A1 | Therapeutic Agent for Type 2 Diabetes | RNASE1, CDKL2, CDKL1 | HSD17B10 3806/4885SLC6A3 3762/4885SLC6A2 4046/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.