Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.39 |
| ▸ | FURIN | P09958 | 3/20 | 0.39 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | SIRT2 | Q8IXJ6 | 5/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.36 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15669246 | 0.97 | FURIN (0.40) | PSMB5FURINSSTR3HTR2APTPN1 | |
| SCHEMBL29723475 | 0.97 | FURIN (0.40) | PSMB5FURINSSTR3HTR2APTPN1 | |
| SCHEMBL17541309 | 0.94 | KLK7 (0.38) | PSMB5FURINSSTR3PTPN1SIRT2 | |
| SCHEMBL29414597 | 0.94 | HTR2A (0.40) | FURINSSTR3HTR2APTPN1SIRT2 | |
| SCHEMBL2734925 | 0.94 | HTR2A (0.40) | FURINSSTR3HTR2APTPN1SIRT2 | |
| SCHEMBL19731720 | 0.94 | HTR2A (0.40) | FURINSSTR3HTR2APTPN1SIRT2 | |
| SCHEMBL12094377 | 0.94 | HTR2A (0.40) | FURINSSTR3HTR2APTPN1SIRT2 | |
| SCHEMBL12944195 | 0.94 | HTR2A (0.40) | FURINSSTR3HTR2APTPN1SIRT2 | |
| SCHEMBL29579452 | 0.94 | HTR2A (0.40) | FURINSSTR3HTR2APTPN1SIRT2 | |
| SCHEMBL13830646 | 0.94 | HTR2A (0.40) | FURINSSTR3HTR2APTPN1SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016030791-A1 | STABILITY-MODULATING LINKERS FOR USE WITH ANTIBODY DRUG CONJUGATES | PFIZER INC. (US) | 2016-03-03 | — | — | WO | disclosed |