SCHEMBL29414597

SCHEMBL29414597

CC(C)[C@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)N[C@@H](CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)Oc2ccc([N+](=O)[O-])cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ HTR2A P28223 1/20 0.40
▸ PTPN1 P18031 4/20 0.39
▸ FURIN P09958 2/20 0.39
▸ SSTR3 P32745 1/20 0.38
▸ CASP3 P42574 2/20 0.38
▸ SIRT2 Q8IXJ6 5/20 0.38
▸ SIRT1 Q96EB6 3/20 0.38
▸ SIRT3 Q9NTG7 3/20 0.38
▸ MAP1LC3B Q9GZQ8 1/20 0.37
▸ SIRT5 Q9NXA8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12944195 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL29579452 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL13110590 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL19731720 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL2734925 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL12094377 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL13830646 1.00 HTR2A (0.40) HTR2APTPN1FURINSSTR3CASP3
Trifluoroacetic Acid SCHEMBL31096968 0.96 PTPN1 (0.43) HTR2APTPN1FURINSSTR3CASP3
SCHEMBL15088221 0.96 HTR2A (0.40) HTR2APTPN1SSTR3SIRT2SIRT1
SCHEMBL13311064 0.94 FURIN (0.39) HTR2APTPN1FURINSSTR3SIRT2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 190 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250250342-A2 ANTI-MET ANTIBODIES, BISPECIFIC ANTIGEN BINDING MOLECULES THAT BIND MET, AND METHODS OF USE THEREOF REGENERON PHARMACEUTICALS, INC. 2025-08-07 — — US claimed
CN-118047832-A Anti-MET antibodies that bind MET, bispecific antigen binding molecules, and methods of use thereof 瑞泽恩制药公司 2024-05-17 — — CN claimed
US-20230416376-A1 ANTI-MET ANTIBODIES, BISPECIFIC ANTIGEN BINDING MOLECULES THAT BIND MET, AND METHODS OF USE THEREOF REGENERON PHARMA (US) 2023-12-28 — — US claimed
US-20260144886-A1 TARGETED DRUG CONJUGATE, MEDICINE INCLUDING SAME, AND COMPOUND FUJIFILM CORPORATION (JP) 2026-05-28 — — US disclosed
US-12624109-B2 αv-integrin targeted small molecule drug conjugates TARGETTHERA LLC (US) 2026-05-12 — — US disclosed
WO-2026087536-A1 METHODS OF USING HOMOTAURINE AND ANALOGS THEREOF FOR THE TREATMENT OF GLUCAGON-LIKE PEPTIDE 1 RECEPTOR AGONIST INDUCED GASTROINTESTINAL SIDE EFFECTS UNIVERSITY OF TARTU (EE) 2026-04-30 — — WO disclosed
US-20260097129-A1 ANTIBODY-DRUG CONJUGATE COMPRISING DRUG AND ANTIBODY SPECIFICALLY BINDING TO GRP94 OR ANTIGEN-BINDING FRAGMENT THEREOF UNIV KOOKMIN IND ACAD COOP FOUND (KR) 2026-04-09 — — US disclosed
EP-4721767-A1 ANTI-B7-H3 ANTIBODY OR FRAGMENT THEREOF, AND ANTIBODY DRUG CONJUGATE TARGETING B7-H3 Jiangsu Mabwell Health Pharmaceutical R&D Co., Ltd. (CN) 2026-04-08 — — EP disclosed
US-12570610-B2 Macromolecule-supported aminobenzazepine compounds BOLT BIOTHERAPEUTICS, INC. (US) 2026-03-10 — — US disclosed
CN-121586588-A Targeted drug complexes, and pharmaceutical products and compounds comprising the same 富士胶片株式会社 2026-02-27 — — CN disclosed
US-20260053939-A1 Combination Therapy for Cancer GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) 2026-02-26 — — US disclosed
CN-109790178-B Novel cytotoxic agents and conjugates thereof 宝力泰锐克斯有限公司 2022-05-03 — — CN disclosed
WO-2022086853-A1 STAR POLYMER DRUG CONJUGATES AVIDEA TECHNOLOGIES, INC. (US) 2022-04-28 — — WO disclosed
EP-3980423-A1 5H-PYRROLO[3,2-D]PYRIMIDINE-2,4-DIAMINO COMPOUNDS AND ANTIBODY CONJUGATES THEREOF Sutro Biopharma, Inc. (US) 2022-04-13 — — EP disclosed
EP-3980080-A1 IMMUNOMODULATOR ANTIBODY DRUG CONJUGATES AND USES THEREOF Sutro Biopharma, Inc. (US) 2022-04-13 — — EP disclosed
CN-114272389-A Eribulin-based antibody-drug conjugates and methods of use 卫材研究发展管理有限公司 2022-04-05 — — CN disclosed
WO-2022067224-A1 COMPOSITION AND USE OF ALTERNATIVELY FORMATTED ANTI-MESOTHELIN ANTIBODIES FOR THE TREATMENT OF CANCER Navrogen, Inc. (US) 2022-03-31 — — WO disclosed
CN-114191563-A Eribulin-based antibody-drug conjugates and methods of use 卫材研究发展管理有限公司 2022-03-18 — — CN disclosed
CN-114191428-A Eribulin-based antibody-drug conjugates and methods of use 卫材研究发展管理有限公司 2022-03-18 — — CN disclosed
US-20220072137-A1 LINKER FOR ANTIBODY-DRUG CONJUGATES AND ITS USE REMEGEN CO., LTD. (CN) 2022-03-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260053939-A1 Combination Therapy for Cancer BCL6, PSMB6, PDCD6 HTR2A 4727/4885PTPN1 443/4885FURIN 4825/4885
US-20260097129-A1 ANTIBODY-DRUG CONJUGATE COMPRISING DRUG AND ANTIBODY SPECIFICALLY BINDING TO GRP94 OR ANTIGEN-BINDING FRAGMENT THEREOF FCGR2A, HACD3, FCER2 HTR2A 2807/4885PTPN1 2027/4885FURIN 4645/4885
US-20250250342-A2 ANTI-MET ANTIBODIES, BISPECIFIC ANTIGEN BINDING MOLECULES THAT BIND MET, AND METHODS OF USE THEREOF MET, HGF, HGFAC HTR2A 1559/4885PTPN1 598/4885FURIN 2633/4885
US-20230416376-A1 ANTI-MET ANTIBODIES, BISPECIFIC ANTIGEN BINDING MOLECULES THAT BIND MET, AND METHODS OF USE THEREOF MET, HGF, HGFAC HTR2A 1559/4885PTPN1 598/4885FURIN 2633/4885
US-12624109-B2 αv-integrin targeted small molecule drug conjugates ITGA1, ITGB1, ITGA2 HTR2A 3448/4885PTPN1 2335/4885FURIN 3063/4885
US-12570610-B2 Macromolecule-supported aminobenzazepine compounds BCL6, CLTB, MET HTR2A 1107/4885PTPN1 3340/4885FURIN 1525/4885
US-20220072137-A1 LINKER FOR ANTIBODY-DRUG CONJUGATES AND ITS USE PA2G4, IGSF11, FCGRT HTR2A 3844/4885PTPN1 1681/4885FURIN 1746/4885
US-20260144886-A1 TARGETED DRUG CONJUGATE, MEDICINE INCLUDING SAME, AND COMPOUND SLC43A1, SLC7A1, SLC10A1 HTR2A 2598/4885PTPN1 466/4885FURIN 1224/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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