SCHEMBL17552158

SCHEMBL17552158

Bc1cccc(C(=O)NC2CCCCC2)c1

nearest known ligand 0.68

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.68
NPC1 O15118 4/20 0.68
L3MBTL1 Q9Y468 1/20 0.66
SMN1; SMN2 Q16637 3/20 0.63
HSD17B10 Q99714 2/20 0.63
KDM4E B2RXH2 1/20 0.63
GFER P55789 1/20 0.63
LMNA P02545 1/20 0.60
PKM P14618 1/20 0.59
HPGD P15428 1/20 0.59
HTR2B P41595 1/20 0.59
KDM1A O60341 1/20 0.58
HTT P42858 1/20 0.56
GRM5 P41594 2/20 0.55
ERN1 O75460 1/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9265040 0.89 RAB9A (0.79) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL6707186 0.89 RAB9A (0.79) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL19445791 0.84 RAB9A (0.72) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL26413302 0.83 RAB9A (0.70) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL3037026 0.82 ERN1 (0.65) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL3771488 0.81 RAB9A (0.68) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL6326321 0.81 RAB9A (0.68) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL613993 0.81 RAB9A (0.68) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL21104744 0.81 RAB9A (0.68) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10
SCHEMBL2310568 0.81 RAB9A (0.68) RAB9ANPC1L3MBTL1SMN1; SMN2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180340174-A1 METHOD FOR IDENTIFICATION OF MOLECULES WITH DESIRED CHARACTERISTICS NANOCORE APS (DK) 2018-11-29 US disclosed
EP-3218479-A1 METHOD FOR IDENTIFICATION OF MOLECULES WITH DESIRED CHARACTERISTICS Nanocore ApS (DK) 2017-09-20 EP disclosed
WO-2016074683-A1 METHOD FOR IDENTIFICATION OF MOLECULES WITH DESIRED CHARACTERISTICS LUNDORF PEDERSEN MATERIALS APS (DK) 2016-05-19 WO disclosed
WO-2016033150-A1 SOLUBLE EPOXIDE HYDROLASE INHIBITORS AND USES THEREOF X-CHEM, INC. (US) 2016-03-03 WO disclosed