Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | G6PD | P11413 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8759092 | 0.85 | HPGD (0.40) | KMT2AMEN1POLBG6PDKDM1A | |
| SCHEMBL29531243 | 0.84 | MAPK1 (0.50) | KMT2AMEN1KDM1AHDAC3HDAC1 | |
| SCHEMBL1939816 | 0.84 | MAPK1 (0.50) | KMT2AMEN1KDM1AHDAC3HDAC1 | |
| SCHEMBL13652584 | 0.84 | ALDH1A1 (0.49) | HPGDMAPK1 | |
| SCHEMBL1096891 | 0.79 | GAA (0.50) | KMT2AMEN1POLBKDM1AMAPK1 | |
| SCHEMBL9133028 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1POLBHPGDMAPK1 | |
| SCHEMBL38651149 | 0.77 | ALDH1A1 (0.57) | KMT2AMEN1POLBHPGDMAPK1 | |
| SCHEMBL5360905 | 0.77 | L3MBTL1 (0.58) | KMT2AMEN1HPGDMAPK1 | |
| SCHEMBL17550098 | 0.77 | KDM1A (0.62) | KMT2AMEN1KDM1AHDAC3HPGD | |
| SCHEMBL14677778 | 0.76 | HDAC3 (0.66) | HDAC3HDAC1HDAC2NCOR2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569919-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2012-04-18 | — | — | EP | disclosed |
| US-7642277-B2 | Non-nucleoside reverse transcriptase inhibitors | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-01-05 | — | — | US | disclosed |