Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13953683 | 1.00 | MIF (0.41) | MIF | |
| SCHEMBL443529 | 0.91 | MIF (0.46) | MIF | |
| SCHEMBL21304587 | 0.84 | MIF (0.42) | MIF | |
| SCHEMBL22279374 | 0.84 | MIF (0.42) | MIF | |
| SCHEMBL955932 | 0.83 | CHRNA7 (0.41) | MIF | |
| SCHEMBL955933 | 0.83 | CHRNA7 (0.41) | MIF | |
| SCHEMBL13799939 | 0.83 | CHRNA7 (0.41) | MIF | |
| SCHEMBL957376 | 0.81 | ADRB2 (0.45) | MIF | |
| SCHEMBL16034537 | 0.81 | MIF (0.39) | MIF | |
| SCHEMBL116445 | 0.81 | MIF (0.39) | MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2183229-B1 | SYNTHESIS OF INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 | VITAE PHARMACEUTICALS INC (US) | 2012-04-18 | — | — | EP | disclosed |
| WO-2009134387-A1 | CYCLIC INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1 | VITAE PHARMACEUTICALS, INC. (US) | 2009-11-05 | — | — | WO | disclosed |