Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.48 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.45 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.44 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28408449 | 0.88 | PTGS1 (0.66) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL5961842 | 0.84 | PTGS1 (0.59) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL538512 | 0.84 | KMT2A (0.60) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL2391613 | 0.83 | FFAR1 (0.53) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL29512995 | 0.82 | KMT2A (0.58) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL28594606 | 0.82 | KMT2A (0.58) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL27701716 | 0.82 | KMT2A (0.58) | PTGS1ABCC4LMNAGAATSHR | |
| Hydrochloric Acid SCHEMBL11895689 | 0.82 | KMT2A (0.58) | PTGS1ABCC4LMNAGAATSHR | |
| Ammonia Solution, Strong SCHEMBL27926479 | 0.82 | KMT2A (0.58) | PTGS1ABCC4LMNAGAATSHR | |
| SCHEMBL8645744 | 0.82 | PTGS1 (0.55) | PTGS1ABCC4LMNAGAATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103382154-B | Synthetic method of methyl 4'-bromomethylbiphenyl-2-carboxylate | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD | 2015-01-21 | — | — | CN | claimed |
| CN-103382154-A | Synthetic method of methyl 4'-bromomethylbiphenyl-2-carboxylate | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD | 2013-11-06 | — | — | CN | claimed |
| CN-103382154-B | Synthetic method of methyl 4'-bromomethylbiphenyl-2-carboxylate | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD | 2015-01-21 | — | — | CN | disclosed |
| CN-103382154-A | Synthetic method of methyl 4'-bromomethylbiphenyl-2-carboxylate | SHANDONG JINCHENG PHARMACEUTICAL & CHEMICAL CO LTD | 2013-11-06 | — | — | CN | disclosed |
| WO-2012028925-A2 | AN IMPROVED PROCESS FOR THE PREPARATION OF TELMISARTAN | OGENE SYSTEMS (I) PVT LTD (IN) | 2012-03-08 | — | — | WO | disclosed |
| US-5274104-A | N-substituted heterocyclic derivatives useful in the treatment of cardiovascular disorders | ELF SANOFI, A FRENCH CORP. (FR) | 1993-12-28 | — | — | US | disclosed |