SCHEMBL17554154

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL17554043	0.89	POLB (0.77)	NR1H4PPARGPOLBKDM4EHSD17B10
	SCHEMBL17554103	0.86	ALDH1A1 (0.72)	NR1H4POLB
	SCHEMBL30560594	0.86	ALDH1A1 (0.72)	NR1H4POLB
	SCHEMBL17554074	0.84	HTR1A (0.66)	NR1H4SLC6A4SLC6A2DRD3HTR1A
	SCHEMBL17554050	0.83	KDM4E (0.68)	PPARGPOLBSLC6A4DRD3DRD2
	SCHEMBL10724572	0.83	DRD3 (0.78)	SLC6A4SLC6A2DRD3HTR1AADRA2A
	SCHEMBL17554159	0.82	CYP1A2 (0.78)	NR1H4PPARGPOLBHTR1A
	SCHEMBL17554040	0.81	BCL3 (0.78)	POLBKDM4EHSD17B10
	SCHEMBL30560619	0.81	BCL3 (0.78)	POLBKDM4EHSD17B10
	SCHEMBL17554076	0.80	POLB (0.67)	POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.