SCHEMBL17554244

SCHEMBL17554244

O=C(O)Oc1ccc2c(c1)C(=O)c1ccccc1-2

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.53
PTPRC P08575 2/20 0.51
MAPT P10636 5/20 0.48
ALDH1A1 P00352 4/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
BCL2 P10415 1/20 0.47
MCL1 Q07820 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.46
ACE2 Q9BYF1 1/20 0.45
KMT2A Q03164 2/20 0.45
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
LMNA P02545 1/20 0.44
ELANE P08246 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
TSHR P16473 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
HTR7 P34969 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3912083 0.98 TTR (0.55) TTRPTPRCMAPTALDH1A1SMN1; SMN2
SCHEMBL6261936 0.96 PTPRC (0.56) TTRPTPRCMAPTALDH1A1SMN1; SMN2
SCHEMBL6260079 0.93 PTPRC (0.56) TTRPTPRCMAPTALDH1A1SMN1; SMN2
SCHEMBL10526608 0.93 MAPT (0.49) TTRPTPRCMAPTALDH1A1SMN1; SMN2
SCHEMBL8900788 0.93 MAPT (0.51) TTRPTPRCMAPTALDH1A1SMN1; SMN2
SCHEMBL4642778 0.88 MAPT (0.61) TTRPTPRCMAPTALDH1A1SMN1; SMN2
SCHEMBL15085173 0.86 MAPT (0.62) TTRMAPTALDH1A1SMN1; SMN2BCL2
SCHEMBL10529319 0.84 MAPT (0.49) MAPTALDH1A1SMN1; SMN2L3MBTL1KMT2A
SCHEMBL28482981 0.84 MEN1 (0.53) TTRPTPRCMAPTALDH1A1SMN1; SMN2
SCHEMBL10528839 0.83 S100A4 (0.55) MAPTALDH1A1SMN1; SMN2L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1993989-B1 POLYCARBOXYLIC ACID PRODUCTION SYSTEM EMPLOYING OXIDATIVE DIGESTION WITH REDUCED OR ELIMINATED UPSTREAM LIQUOR EXCHANGE GRUPO PETROTEMEX SA DE CV (MX) 2018-11-07 EP claimed
EP-1989164-B1 POLYCARBOXYLIC ACID PRODUCTION SYSTEM EMPLOYING COOLED MOTHER LIQUOR FROM OXIDATIVE DIGESTION AS FEED TO IMPURITY PURGE SYSTEM GRUPO PETROTEMEX SA DE CV (MX) 2018-02-14 EP claimed
EP-2574606-B1 Polycarboxylic acid production system employing cooled mother liquor from oxidative digestion as feed to impurity purge system GRUPO PETROTEMEX SA DE CV (MX) 2016-09-28 EP claimed
EP-1084454-B1 FREE-FORM NANOFABRICATION USING MULTI-PHOTON EXCITATION UNIV CONNECTICUT (US) 2016-03-09 EP claimed