Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10526608 | 0.96 | MAPT (0.49) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL17554244 | 0.93 | TTR (0.53) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10529319 | 0.91 | MAPT (0.49) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL3912083 | 0.90 | TTR (0.55) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10528839 | 0.89 | S100A4 (0.55) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6261936 | 0.89 | PTPRC (0.56) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10526615 | 0.87 | S100A4 (0.53) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL22336250 | 0.86 | MAPT (0.55) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10528826 | 0.85 | MAPT (0.41) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL10529310 | 0.85 | MAPT (0.54) | MAPTL3MBTL1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0147226-B1 | VISIBLE LIGHT ABSORBING PEROXY ESTERS | LOCTITE CORPORATION (US) | 1989-11-23 | — | — | EP | claimed |
| EP-0663391-B1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | HOFFMANN LA ROCHE (CH) | 1997-04-09 | — | — | EP | disclosed |
| EP-0663391-A1 | Sulphuric acid esters of sugar alcohols for the treatment of arteriosclerotic changes in the vascular walls | F. HOFFMANN-LA ROCHE AG (CH) | 1995-07-19 | — | — | EP | disclosed |